{"product_id":"new-product-570752","title":"SDHB Polyclonal Antibody","description":"\u003cp\u003eComplex II of the respiratory chain, which is specifically involved in the oxidation of succinate, carries electrons from FADH to CoQ. The complex is composed of four nuclear-encoded subunits and is localized in the mitochondrial inner membrane. The iron-sulfur subunit is highly conserved and contains three cysteine-rich clusters which may comprise the iron-sulfur centers of the enzyme. Sporadic and familial mutations in this gene result in paragangliomas and pheochromocytoma, and support a link between mitochondrial dysfunction and tumorigenesis.\u003c\/p\u003e\n\u003cp\u003eThe SDHB Polyclonal Antibody is a highly specific and sensitive antibody designed for the detection of SDHB protein in various biological samples. This antibody is produced by immunizing rabbits with a synthetic peptide corresponding to the C-terminal region of human SDHB protein. The resulting polyclonal antibody has been extensively validated for its specificity and sensitivity in various applications, including Western blotting, immunohistochemistry, and immunofluorescence.\u003cbr\u003e\u003cbr\u003eThe SDHB Polyclonal Antibody is a valuable tool for researchers studying the role of SDHB in various biological processes, including cellular respiration, metabolism, and tumorigenesis. This antibody has been shown to detect endogenous levels of SDHB protein in a variety of cell lines and tissues, making it an ideal choice for both basic research and clinical applications.\u003cbr\u003e\u003cbr\u003eIn addition to its high specificity and sensitivity, the SDHB Polyclonal Antibody is also highly versatile and can be used in a variety of experimental conditions. This antibody has been shown to work well with a variety of sample types, including tissue lysates, cell lysates, and purified proteins. It is also compatible with a variety of detection methods, including chemiluminescence, fluorescence, and colorimetric detection.\u003cbr\u003e\u003cbr\u003eOverall, the SDHB Polyclonal Antibody is a reliable and effective tool for the detection of SDHB protein in various biological samples. Its high specificity, sensitivity, and versatility make it an ideal choice for researchers studying the role of SDHB in various biological processes.\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"100ul \/ Rabbit \/ Primary antibody","offer_id":47542705389848,"sku":"BT-AP08181","price":275.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/BT_Lab_2524d9a9-1886-4402-ae4e-7d9a56b6aff3.png?v=1705637410","url":"https:\/\/danabiosci.com\/products\/new-product-570752","provider":"Dana Bioscience","version":"1.0","type":"link"}