{"product_id":"new-product-570735","title":"Sar1B Polyclonal Antibody","description":"\u003cp\u003eThe protein encoded by SAR1B (secretion associated Ras related GTPase 1B) is a small GTPase that acts as a homodimer. The encoded protein is activated by the guanine nucleotide exchange factor PREB and is involved in protein transport from the endoplasmic reticulum to the Golgi. This protein is part of the COPII coat complex. Defects in SAR1B are a cause of chylomicron retention disease (CMRD), also known as Anderson disease (ANDD). Two transcript variants encoding the same protein have been found for this gene.\u003c\/p\u003e\n\u003cp\u003eThe Sar1B Polyclonal Antibody is a highly specific and reliable tool for the detection and analysis of Sar1B protein expression in various biological samples. This antibody has been meticulously developed and rigorously validated to ensure optimal performance and accuracy in a wide range of applications, including Western blotting, immunohistochemistry, and immunofluorescence.\u003cbr\u003e\u003cbr\u003eThe Sar1B protein plays a crucial role in the regulation of vesicular trafficking and protein transport between the endoplasmic reticulum (ER) and the Golgi apparatus. It is an essential component of the COPII coat complex, which is responsible for the formation of transport vesicles that mediate the export of newly synthesized proteins from the ER to the Golgi.\u003cbr\u003e\u003cbr\u003eThe Sar1B Polyclonal Antibody has been generated using high-quality immunogens and state-of-the-art immunization techniques. It exhibits exceptional specificity towards Sar1B, with minimal cross-reactivity to other related proteins. This ensures reliable and accurate detection of Sar1B expression levels in complex biological samples.\u003cbr\u003e\u003cbr\u003eThis antibody has been extensively validated using a variety of experimental approaches, including siRNA knockdown, overexpression, and immunofluorescence colocalization studies. It has consistently demonstrated high sensitivity and specificity, enabling precise quantification and localization of Sar1B protein in different cell types and tissues.\u003cbr\u003e\u003cbr\u003eThe Sar1B Polyclonal Antibody is supplied as a ready-to-use solution, eliminating the need for time-consuming and error-prone antibody preparation. It is provided in a convenient format, allowing for easy storage and handling. The antibody is also available in different sizes to accommodate various experimental requirements.\u003cbr\u003e\u003cbr\u003eIn summary, the Sar1B Polyclonal Antibody is a reliable and highly specific tool for the detection and analysis of Sar1B protein expression. Its exceptional performance and versatility make it an invaluable asset for researchers studying vesicular trafficking, protein transport, and related cellular processes.\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"100ul \/ Rabbit \/ Primary antibody","offer_id":47542698737944,"sku":"BT-AP08130","price":275.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/BT_Lab_9665a7b9-983c-4ddd-a74d-583f63cc353c.png?v=1705637312","url":"https:\/\/danabiosci.com\/products\/new-product-570735","provider":"Dana Bioscience","version":"1.0","type":"link"}