{"product_id":"new-product-570490","title":"Raf-B Polyclonal Antibody","description":"\u003cp\u003eBRAF (B-Raf proto-oncogene, serine\/threonine kinase) encodes a protein belonging to the raf\/mil family of serine\/threonine protein kinases. This protein plays a role in regulating the MAP kinase\/ERKs signaling pathway, which affects cell division, differentiation, and secretion. Mutations in BRAF are associated with cardiofaciocutaneous syndrome, a disease characterized by heart defects, mental retardation and a distinctive facial appearance. Mutations in BRAF have also been associated with various cancers, including non-Hodgkin lymphoma, colorectal cancer, malignant melanoma, thyroid carcinoma, non-small cell lung carcinoma, and adenocarcinoma of lung. A pseudogene, which is located on chromosome X, has been identified for BRAF.\u003c\/p\u003e\n\u003cp\u003eThe Raf-B Polyclonal Antibody is a highly specific and sensitive antibody that has been developed for the detection of Raf-B protein in various biological samples. This antibody has been extensively validated for its specificity and sensitivity in Western blotting, immunohistochemistry, and immunofluorescence applications. \u003cbr\u003e\u003cbr\u003eThe Raf-B protein is a member of the Raf family of serine\/threonine kinases that play a crucial role in the regulation of cell growth, differentiation, and survival. The Raf-B protein is expressed in a wide range of tissues and is involved in various signaling pathways, including the MAPK\/ERK pathway. \u003cbr\u003e\u003cbr\u003eThe Raf-B Polyclonal Antibody has been produced using high-quality immunogens and has undergone rigorous quality control measures to ensure its specificity and sensitivity. This antibody has been shown to detect endogenous levels of Raf-B protein in various cell lines and tissues. \u003cbr\u003e\u003cbr\u003eThis antibody is supplied as a liquid formulation and is suitable for use in a variety of applications, including Western blotting, immunohistochemistry, and immunofluorescence. It is recommended to optimize the antibody concentration and incubation time for each specific application. \u003cbr\u003e\u003cbr\u003eIn summary, the Raf-B Polyclonal Antibody is a reliable and sensitive tool for the detection of Raf-B protein in various biological samples. Its high specificity and sensitivity make it an ideal choice for researchers studying the role of Raf-B in cellular signaling pathways and disease processes.\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"100ul \/ Rabbit \/ Primary antibody","offer_id":47542636577048,"sku":"BT-AP07632","price":275.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/BT_Lab_2222195e-3445-4702-bff5-1535b10357a0.png?v=1705635955","url":"https:\/\/danabiosci.com\/products\/new-product-570490","provider":"Dana Bioscience","version":"1.0","type":"link"}