{"product_id":"new-product-570489","title":"Raf-B Polyclonal Antibody","description":"\u003cp\u003eBRAF (B-Raf proto-oncogene, serine\/threonine kinase) encodes a protein belonging to the raf\/mil family of serine\/threonine protein kinases. This protein plays a role in regulating the MAP kinase\/ERKs signaling pathway, which affects cell division, differentiation, and secretion. Mutations in BRAF are associated with cardiofaciocutaneous syndrome, a disease characterized by heart defects, mental retardation and a distinctive facial appearance. Mutations in BRAF have also been associated with various cancers, including non-Hodgkin lymphoma, colorectal cancer, malignant melanoma, thyroid carcinoma, non-small cell lung carcinoma, and adenocarcinoma of lung. A pseudogene, which is located on chromosome X, has been identified for BRAF.\u003c\/p\u003e\n\u003cp\u003eThe Raf-B Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and analysis of Raf-B protein expression in various biological samples. This antibody is produced through a rigorous process of immunization using a recombinant protein corresponding to the full-length Raf-B protein. It has been extensively validated for its specificity and sensitivity, ensuring reliable and accurate results.\u003cbr\u003e\u003cbr\u003eThe Raf-B Polyclonal Antibody exhibits exceptional performance in various applications, including Western blotting, immunohistochemistry, and immunofluorescence. It recognizes endogenous levels of Raf-B protein in a wide range of species, making it a versatile tool for researchers working with different model organisms.\u003cbr\u003e\u003cbr\u003eWith its high affinity and low background, this antibody enables precise and reliable detection of Raf-B protein expression in both normal and disease states. It provides researchers with valuable insights into the role of Raf-B in various cellular processes, including cell proliferation, differentiation, and survival.\u003cbr\u003e\u003cbr\u003eThe Raf-B Polyclonal Antibody is supplied as a liquid formulation, ensuring ease of use and convenience. It is available in different sizes to accommodate various experimental needs. Each batch of this antibody undergoes strict quality control measures to ensure consistent performance and reproducibility.\u003cbr\u003e\u003cbr\u003eIn summary, the Raf-B Polyclonal Antibody is a reliable and efficient tool for the detection and analysis of Raf-B protein expression. Its high specificity, sensitivity, and versatility make it an invaluable asset for researchers in the field of cellular signaling and cancer biology.\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"100ul \/ Rabbit \/ Primary antibody","offer_id":47542636478744,"sku":"BT-AP07631","price":275.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/BT_Lab_96f503dc-176d-43a8-8e32-65f47c6795f6.png?v=1705635948","url":"https:\/\/danabiosci.com\/products\/new-product-570489","provider":"Dana Bioscience","version":"1.0","type":"link"}