{"product_id":"new-product-570393","title":"PSMD2 Polyclonal Antibody","description":"\u003cp\u003eThe 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP\/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. PSMD12 encodes a non-ATPase subunit of the 19S regulator. A pseudogene has been identified on chromosome 3. Alternatively spliced transcript variants encoding different isoforms have been found for PSMD12.\u003c\/p\u003e\n\u003cp\u003eThe PSMD2 Polyclonal Antibody is a highly specific and sensitive antibody designed for the detection of PSMD2 protein in various biological samples. This antibody is produced by immunizing rabbits with a synthetic peptide corresponding to the C-terminal region of human PSMD2 protein. The PSMD2 Polyclonal Antibody has been extensively validated for its specificity and sensitivity in Western blotting, immunohistochemistry, and immunofluorescence assays. It recognizes a single band of approximately 45 kDa in Western blotting and shows a strong signal in the cytoplasm of cells in immunohistochemistry and immunofluorescence assays.\u003c\/p\u003e\n\u003cp\u003eThis antibody is suitable for use in various research applications, including protein-protein interaction studies, protein degradation assays, and cancer research. The PSMD2 Polyclonal Antibody is supplied as a purified IgG fraction and is available in different sizes to meet the needs of different research projects. With its high specificity and sensitivity, this antibody is an essential tool for researchers studying the PSMD2 protein and its functions in various biological processes.\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"100ul \/ Rabbit \/ Primary antibody","offer_id":47542617145624,"sku":"BT-AP07461","price":275.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/BT_Lab_512d415e-de5c-4a6d-8750-184ed04401dc.png?v=1705635395","url":"https:\/\/danabiosci.com\/products\/new-product-570393","provider":"Dana Bioscience","version":"1.0","type":"link"}