{"product_id":"new-product-570182","title":"PHKA1\/2 Polyclonal Antibody","description":"\u003cp\u003ePhosphorylase kinase is a polymer of 16 subunits, four each of alpha, beta, gamma and delta. The alpha subunit includes the skeletal muscle and hepatic isoforms, and the skeletal muscle isoform is encoded by PHKA1 (phosphorylase kinase regulatory subunit alpha 1). The beta subunit is the same in both the muscle and hepatic isoforms, and encoded by one gene. The gamma subunit also includes the skeletal muscle and hepatic isoforms, which are encoded by two different genes. The delta subunit is a calmodulin and can be encoded by three different genes. The gamma subunits contain the active site of the enzyme, whereas the alpha and beta subunits have regulatory functions controlled by phosphorylation. The delta subunit mediates the dependence of the enzyme on calcium concentration. Mutations in PHKA1 cause glycogen storage disease type 9D, also known as X-linked muscle glycogenosis. Alternatively spliced transcript variants encoding different isoforms have been identified in this gene. A pseudogene has been found on chromosome 1.\u003c\/p\u003e\n\u003cp\u003eThe PHKA1\/2 Polyclonal Antibody is a highly specific and sensitive antibody designed for use in various research applications. This antibody is produced using high-quality polyclonal antibodies that have been purified and validated to ensure optimal performance. The PHKA1\/2 Polyclonal Antibody is specifically designed to target the PHKA1\/2 protein, which is involved in glycogen metabolism. This antibody is suitable for use in a variety of applications, including Western blotting, immunohistochemistry, and immunofluorescence. The PHKA1\/2 Polyclonal Antibody is a reliable and effective tool for researchers studying glycogen metabolism and related pathways. With its high specificity and sensitivity, this antibody is an essential component of any research project focused on this important area of biology.\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"100ul \/ Rabbit \/ Primary antibody","offer_id":47542581002520,"sku":"BT-AP07121","price":275.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/BT_Lab_c70b23bb-ee10-4223-b8a2-9205200b5937.png?v=1705634193","url":"https:\/\/danabiosci.com\/products\/new-product-570182","provider":"Dana Bioscience","version":"1.0","type":"link"}