{"product_id":"new-product-570126","title":"PDX-1 Polyclonal Antibody","description":"\u003cp\u003eThe protein encoded by PDX1 is a transcriptional activator of several genes, including insulin, somatostatin, glucokinase, islet amyloid polypeptide, and glucose transporter type 2. The encoded nuclear protein is involved in the early development of the pancreas and plays a major role in glucose-dependent regulation of insulin gene expression. Defects in this gene are a cause of pancreatic agenesis, which can lead to early-onset insulin-dependent diabetes mellitus (NIDDM), as well as maturity onset diabetes of the young type 4 (MODY4).\u003c\/p\u003e\n\u003cp\u003eThe PDX-1 Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and analysis of pancreatic and duodenal homeobox 1 (PDX-1) protein. This antibody is produced using advanced immunization techniques, resulting in a high affinity and purity. \u003cbr\u003e\u003cbr\u003eThe PDX-1 Polyclonal Antibody exhibits exceptional performance in various applications, including Western blotting, immunohistochemistry, and immunofluorescence. It enables researchers to investigate the expression and localization of PDX-1 protein in different tissues and cell types with utmost precision and accuracy. \u003cbr\u003e\u003cbr\u003eWith its superior sensitivity, this antibody allows for the detection of even low levels of PDX-1 protein, making it an invaluable tool for studying pancreatic development, diabetes, and other related diseases. Its reliable and reproducible results ensure consistent and robust data analysis. \u003cbr\u003e\u003cbr\u003eThe PDX-1 Polyclonal Antibody is supplied in a convenient and ready-to-use format, ensuring ease of use and saving valuable time in the laboratory. It is rigorously tested to meet the highest quality standards, guaranteeing optimal performance and reliability. \u003cbr\u003e\u003cbr\u003eChoose the PDX-1 Polyclonal Antibody for your research needs and unlock new insights into the role of PDX-1 protein in pancreatic function and disease pathogenesis.\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"100ul \/ Rabbit \/ Primary antibody","offer_id":47542574481688,"sku":"BT-AP07039","price":275.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/BT_Lab_e404d89e-2623-4b27-9010-6391c73858b7.png?v=1705633870","url":"https:\/\/danabiosci.com\/products\/new-product-570126","provider":"Dana Bioscience","version":"1.0","type":"link"}