{"product_id":"new-product-570122","title":"PDK2 Polyclonal Antibody","description":"\u003cp\u003ePDK2 encodes a member of the pyruvate dehydrogenase kinase family. Pyruvate dehydrogenase kinase 2 phosphorylates pyruvate dehydrogenase, down-regulating the activity of the mitochondrial pyruvate dehydrogenase complex. Overexpression of PDK2 may play a role in both cancer and diabetes. Alternatively spliced transcript variants encoding multiple isoforms have been observed for PDK2.\u003c\/p\u003e\n\u003cp\u003eThe PDK2 Polyclonal Antibody is a highly specific and reliable tool designed for the detection and quantification of pyruvate dehydrogenase kinase 2 (PDK2) protein in various biological samples. This antibody is produced using state-of-the-art technology, ensuring exceptional quality and performance.\u003cbr\u003e\u003cbr\u003ePDK2 is a crucial enzyme involved in the regulation of glucose metabolism and energy production. It plays a pivotal role in the inhibition of pyruvate dehydrogenase complex (PDC), which is responsible for the conversion of pyruvate to acetyl-CoA. Dysregulation of PDK2 has been implicated in various metabolic disorders, including diabetes, obesity, and cancer.\u003cbr\u003e\u003cbr\u003eThe PDK2 Polyclonal Antibody exhibits high specificity and sensitivity, enabling accurate detection of PDK2 protein levels in both research and clinical settings. It has been extensively validated for various applications, including Western blotting, immunohistochemistry, and immunofluorescence.\u003cbr\u003e\u003cbr\u003eThis antibody is manufactured using high-quality materials and undergoes rigorous quality control procedures to ensure batch-to-batch consistency and reproducibility. It is supplied as a liquid formulation, ready for immediate use, and is compatible with a wide range of experimental conditions.\u003cbr\u003e\u003cbr\u003eWith its exceptional performance and reliability, the PDK2 Polyclonal Antibody is an indispensable tool for researchers and clinicians studying the role of PDK2 in metabolic disorders and exploring potential therapeutic interventions.\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"100ul \/ Rabbit \/ Primary antibody","offer_id":47542573924632,"sku":"BT-AP07031","price":275.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/BT_Lab_05df0596-888b-4f1b-8276-d23c2308d9ab.png?v=1705633853","url":"https:\/\/danabiosci.com\/products\/new-product-570122","provider":"Dana Bioscience","version":"1.0","type":"link"}