{"product_id":"new-product-570064","title":"PARP-1 Polyclonal Antibody","description":"\u003cp\u003ePARP1 (poly(ADP-ribose) polymerase 1) encodes a chromatin-associated enzyme, poly(ADP-ribosyl)transferase, which modifies various nuclear proteins by poly(ADP-ribosyl)ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, this enzyme may be the site of mutation in Fanconi anemia, and may participate in the pathophysiology of type I diabetes.\u003c\/p\u003e\n\u003cp\u003eThe PARP-1 Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and quantification of PARP-1 protein in various biological samples. This antibody has been extensively validated and exhibits exceptional performance in a wide range of applications, including Western blotting, immunohistochemistry, and immunofluorescence.\u003cbr\u003e\u003cbr\u003ePARP-1, also known as poly(ADP-ribose) polymerase 1, is a nuclear enzyme involved in DNA repair and maintenance of genomic stability. It plays a crucial role in cellular processes such as DNA damage response, apoptosis, and transcriptional regulation. Dysregulation of PARP-1 has been implicated in various diseases, including cancer, neurodegenerative disorders, and cardiovascular diseases.\u003cbr\u003e\u003cbr\u003eThe PARP-1 Polyclonal Antibody is produced using high-quality immunogens and advanced purification techniques to ensure maximum specificity and sensitivity. It has been rigorously tested to ensure minimal cross-reactivity with other proteins, providing reliable and accurate results. The antibody exhibits excellent affinity and binding capacity, enabling efficient detection of PARP-1 protein even at low concentrations.\u003cbr\u003e\u003cbr\u003eThis antibody is supplied as a liquid formulation in a convenient size, allowing for easy handling and storage. It is provided in a ready-to-use format, eliminating the need for time-consuming preparation steps. The PARP-1 Polyclonal Antibody is compatible with various detection systems and can be used in combination with secondary antibodies for enhanced signal amplification.\u003cbr\u003e\u003cbr\u003eWith its exceptional performance and reliability, the PARP-1 Polyclonal Antibody is an indispensable tool for researchers and scientists studying PARP-1 biology and its involvement in various cellular processes and diseases. Its high specificity, sensitivity, and versatility make it an ideal choice for a wide range of applications, facilitating accurate and reproducible results.\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"100ul \/ Rabbit \/ Primary antibody","offer_id":47542566846744,"sku":"BT-AP06934","price":275.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/BT_Lab_12773572-1ed5-4c40-b9fb-85e438bc9c44.png?v=1705633504","url":"https:\/\/danabiosci.com\/products\/new-product-570064","provider":"Dana Bioscience","version":"1.0","type":"link"}