{"product_id":"new-product-569544","title":"NFKappaB-p65 (Acetyl Lys221) Polyclonal Antibody","description":"\u003cp\u003eNF-kappa-B is a ubiquitous transcription factor involved in several biological processes. It is held in the cytoplasm in an inactive state by specific inhibitors. Upon degradation of the inhibitor, NF-kappa-B moves to the nucleus and activates transcription of specific genes. NF-kappa-B is composed of NFKB1 or NFKB2 bound to either REL, RELA, or RELB. The most abundant form of NF-kappa-B is NFKB1 complexed with the product of this gene, RELA. Four transcript variants encoding different isoforms have been found for RELA.\u003c\/p\u003e\n\u003cp\u003eThe NFKappaB-p65 (Acetyl Lys221) Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and quantification of NFKappaB-p65 protein in various biological samples. This antibody has been extensively validated and exhibits exceptional performance in a wide range of applications, including Western blotting, immunohistochemistry, and immunofluorescence.\u003cbr\u003e\u003cbr\u003eThe NFKappaB-p65 (Acetyl Lys221) Polyclonal Antibody is produced using state-of-the-art techniques, ensuring high purity and batch-to-batch consistency. It is derived from a host animal that has been immunized with a synthetic peptide corresponding to the acetylated lysine 221 region of the NFKappaB-p65 protein. This antibody specifically recognizes the acetylated form of NFKappaB-p65, enabling precise detection and analysis of post-translational modifications.\u003cbr\u003e\u003cbr\u003eWith its exceptional sensitivity, this antibody allows for the detection of low-abundance NFKappaB-p65 protein levels, making it an invaluable tool for researchers studying the intricate regulatory mechanisms involving NFKappaB-p65. Its high specificity ensures minimal cross-reactivity with other proteins, providing reliable and accurate results.\u003cbr\u003e\u003cbr\u003eThe NFKappaB-p65 (Acetyl Lys221) Polyclonal Antibody is supplied as a liquid formulation, ready for immediate use. It is provided in a convenient size, allowing for multiple experiments without the need for frequent reordering. Each batch is accompanied by a detailed datasheet, providing comprehensive information on the antibody's performance characteristics and recommended experimental conditions.\u003cbr\u003e\u003cbr\u003eIn summary, the NFKappaB-p65 (Acetyl Lys221) Polyclonal Antibody is a superior research tool that offers exceptional sensitivity, specificity, and reliability. Its application in various experimental techniques makes it an indispensable asset for scientists investigating the role of NFKappaB-p65 in cellular processes and disease mechanisms.\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"100ul \/ Rabbit \/ Primary antibody","offer_id":47542444228888,"sku":"BT-AP05985","price":275.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/BT_Lab_45f2eb91-7b4e-40d6-bde8-2e236f7249cf.png?v=1705630731","url":"https:\/\/danabiosci.com\/products\/new-product-569544","provider":"Dana Bioscience","version":"1.0","type":"link"}