{"product_id":"new-product-569542","title":"NFKappaB-p65 (Acetyl Lys122) Polyclonal Antibody","description":"\u003cp\u003eNF-kappa-B is a ubiquitous transcription factor involved in several biological processes. It is held in the cytoplasm in an inactive state by specific inhibitors. Upon degradation of the inhibitor, NF-kappa-B moves to the nucleus and activates transcription of specific genes. NF-kappa-B is composed of NFKB1 or NFKB2 bound to either REL, RELA, or RELB. The most abundant form of NF-kappa-B is NFKB1 complexed with the product of this gene, RELA. Four transcript variants encoding different isoforms have been found for RELA.\u003c\/p\u003e\n\u003cp\u003eThe NFKappaB-p65 (Acetyl Lys122) Polyclonal Antibody is a highly specific and sensitive tool for the detection and quantification of NFKappaB-p65 protein in various biological samples. This antibody has been developed using advanced immunization techniques and exhibits excellent affinity and selectivity towards the acetylated form of Lys122 on the NFKappaB-p65 protein.\u003cbr\u003e\u003cbr\u003eThe NFKappaB-p65 protein plays a crucial role in the regulation of numerous cellular processes, including inflammation, immune response, and cell survival. The acetylation of Lys122 on NFKappaB-p65 has been shown to modulate its transcriptional activity and influence downstream gene expression. Therefore, the ability to accurately measure the acetylation status of NFKappaB-p65 is of great importance in understanding its functional role in various biological contexts.\u003cbr\u003e\u003cbr\u003eThis polyclonal antibody has been rigorously validated for its specificity and sensitivity through various experimental approaches, including Western blotting, immunoprecipitation, and immunofluorescence. It exhibits minimal cross-reactivity with other related proteins, ensuring reliable and accurate results.\u003cbr\u003e\u003cbr\u003eThe NFKappaB-p65 (Acetyl Lys122) Polyclonal Antibody is supplied as a ready-to-use solution, allowing for convenient and efficient application in a wide range of experimental techniques. It is suitable for use in both research and clinical settings, enabling scientists and clinicians to gain valuable insights into the role of NFKappaB-p65 in various disease processes.\u003cbr\u003e\u003cbr\u003eIn summary, the NFKappaB-p65 (Acetyl Lys122) Polyclonal Antibody is a highly reliable and specific tool for the detection and quantification of acetylated NFKappaB-p65 protein. Its exceptional performance and versatility make it an essential component in studies aiming to elucidate the functional significance of NFKappaB-p65 in various biological processes.\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"100ul \/ Rabbit \/ Primary antibody","offer_id":47542444163352,"sku":"BT-AP05983","price":275.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/BT_Lab_74880772-2a69-477a-93fb-ca113591beec.png?v=1705630722","url":"https:\/\/danabiosci.com\/products\/new-product-569542","provider":"Dana Bioscience","version":"1.0","type":"link"}