{"product_id":"new-product-569486","title":"Neuregulin-3 Polyclonal Antibody","description":"\u003cp\u003eNRG3 (neuregulin 3) is a member of the neuregulin gene family. This gene family encodes ligands for the transmembrane tyrosine kinase receptors ERBB3 and ERBB4 - members of the epidermal growth factor receptor family. Ligand binding activates intracellular signaling cascades and the induction of cellular responses including proliferation, migration, differentiation, and survival or apoptosis. This gene encodes neuregulin 3 (NRG3). NRG3 has been shown to activate the tyrosine phosphorylation of its cognate receptor, ERBB4, and is thought to influence neuroblast proliferation, migration and differentiation by signalling through ERBB4. NRG3 also promotes mammary differentiation during embryogenesis. Linkage studies have implicated NRG3 as a susceptibility locus for schizophrenia and schizoaffective disorder. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional transcript variants have been described but their biological validity has not been verified.\u003c\/p\u003e\n\u003cp\u003eThe Neuregulin-3 Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and analysis of Neuregulin-3 protein in various biological samples. This antibody is produced using advanced recombinant DNA technology, ensuring high purity and batch-to-batch consistency.\u003cbr\u003e\u003cbr\u003eNeuregulin-3 is a crucial protein involved in various cellular processes, including cell growth, differentiation, and survival. It plays a significant role in the development and maintenance of the nervous system, as well as in the regulation of cardiac function. The Neuregulin-3 Polyclonal Antibody recognizes and binds to the target protein with exceptional affinity, enabling accurate and reliable detection.\u003cbr\u003e\u003cbr\u003eThis antibody has been extensively validated for its specificity and sensitivity in various experimental techniques, including Western blotting, immunohistochemistry, and immunofluorescence. It exhibits minimal cross-reactivity with other related proteins, ensuring precise and reliable results.\u003cbr\u003e\u003cbr\u003eThe Neuregulin-3 Polyclonal Antibody is supplied as a liquid formulation, ready for immediate use. It is provided in a convenient size and concentration, allowing for easy handling and storage. The antibody is stable under recommended storage conditions, ensuring long-term usability without compromising its performance.\u003cbr\u003e\u003cbr\u003eResearchers and scientists in the fields of neuroscience, developmental biology, and cardiovascular research will greatly benefit from the Neuregulin-3 Polyclonal Antibody. Its exceptional specificity, sensitivity, and reliability make it an indispensable tool for studying the role of Neuregulin-3 in various physiological and pathological processes.\u003cbr\u003e\u003cbr\u003eIn summary, the Neuregulin-3 Polyclonal Antibody is a highly reliable and efficient tool for the detection and analysis of Neuregulin-3 protein. Its exceptional specificity, sensitivity, and stability make it an ideal choice for researchers aiming to unravel the intricate mechanisms underlying Neuregulin-3-mediated cellular processes.\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"100ul \/ Rabbit \/ Primary antibody","offer_id":47542438068504,"sku":"BT-AP05916","price":275.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/BT_Lab_6a971962-0223-446e-b5db-e1cf7aa7b508.png?v=1705630443","url":"https:\/\/danabiosci.com\/products\/new-product-569486","provider":"Dana Bioscience","version":"1.0","type":"link"}