{"product_id":"new-product-569382","title":"N\/H\/K-Ras Polyclonal Antibody","description":"\u003cp\u003eHRAS belongs to the Ras oncogene family, whose members are related to the transforming genes of mammalian sarcoma retroviruses. The products encoded by these genes function in signal transduction pathways. These proteins can bind GTP and GDP, and they have intrinsic GTPase activity. GTPase Hras undergoes a continuous cycle of de- and re-palmitoylation, which regulates its rapid exchange between the plasma membrane and the Golgi apparatus. Mutations in this gene cause Costello syndrome, a disease characterized by increased growth at the prenatal stage, growth deficiency at the postnatal stage, predisposition to tumor formation, mental retardation, skin and musculoskeletal abnormalities, distinctive facial appearance and cardiovascular abnormalities. Defects in this gene are implicated in a variety of cancers, including bladder cancer, follicular thyroid cancer, and oral squamous cell carcinoma. Multiple transcript variants, which encode different isoforms, have been identified for this gene.\u003c\/p\u003e\n\u003cp\u003eThe N\/H\/K-Ras Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and analysis of N-Ras, H-Ras, and K-Ras proteins. This antibody is produced using advanced techniques to ensure high affinity and specificity, making it an ideal choice for various applications in research and diagnostics.\u003cbr\u003e\u003cbr\u003eThe N\/H\/K-Ras Polyclonal Antibody exhibits exceptional performance in Western blotting, immunohistochemistry, and immunofluorescence assays. It recognizes the conserved epitopes of N-Ras, H-Ras, and K-Ras proteins, enabling accurate and reliable detection of these important signaling molecules.\u003cbr\u003e\u003cbr\u003eThis antibody is manufactured under stringent quality control measures to ensure batch-to-batch consistency and reproducibility. It is validated for use in multiple species, including human, mouse, and rat, allowing for versatile applications across different experimental models.\u003cbr\u003e\u003cbr\u003eThe N\/H\/K-Ras Polyclonal Antibody is supplied as a ready-to-use solution, eliminating the need for time-consuming and complex preparation steps. Its high specificity and sensitivity enable the detection of low-abundance N-Ras, H-Ras, and K-Ras proteins, making it an invaluable tool for studying various cellular processes and signaling pathways.\u003cbr\u003e\u003cbr\u003eWith its exceptional performance and reliability, the N\/H\/K-Ras Polyclonal Antibody is an essential reagent for researchers and clinicians working in the fields of cancer biology, cell signaling, and drug discovery. Its ability to accurately detect and analyze N-Ras, H-Ras, and K-Ras proteins makes it an indispensable tool for advancing our understanding of these critical molecules and their roles in disease progression.\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"100ul \/ Rabbit \/ Primary antibody","offer_id":47542407168280,"sku":"BT-AP05746","price":275.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/BT_Lab_f01daa97-a3d1-45ca-a7c4-3b7139c463b0.png?v=1705629901","url":"https:\/\/danabiosci.com\/products\/new-product-569382","provider":"Dana Bioscience","version":"1.0","type":"link"}