{"product_id":"new-product-569341","title":"MVK Polyclonal Antibody","description":"\u003cp\u003eMVK encodes the peroxisomal enzyme mevalonate kinase. Mevalonate is a key intermediate, and mevalonate kinase a key early enzyme, in isoprenoid and sterol synthesis. Mevalonate kinase deficiency caused by mutation of MVK results in mevalonic aciduria, a disease characterized psychomotor retardation, failure to thrive, hepatosplenomegaly, anemia and recurrent febrile crises. Defects in this gene also cause hyperimmunoglobulinaemia D and periodic fever syndrome, a disorder characterized by recurrent episodes of fever associated with lymphadenopathy, arthralgia, gastrointestinal dismay and skin rash. Alternative splicing results in multiple transcript variants.\u003c\/p\u003e\n\u003cp\u003eThe MVK Polyclonal Antibody is a highly specific and sensitive immunological reagent designed for the detection and quantification of mevalonate kinase (MVK) protein in various biological samples. This antibody is produced by immunizing rabbits with a synthetic peptide corresponding to the C-terminal region of human MVK protein. The resulting polyclonal antibody exhibits high affinity and specificity towards MVK protein, making it an ideal tool for various applications such as Western blotting, immunohistochemistry, and ELISA.\u003cbr\u003e\u003cbr\u003eThe MVK Polyclonal Antibody is purified using a combination of protein A and peptide affinity chromatography, ensuring high purity and minimal cross-reactivity with other proteins. This antibody has been extensively validated for its specificity and sensitivity in detecting MVK protein in various human tissues and cell lines. It has also been shown to be highly reproducible and reliable, providing consistent results across multiple experiments.\u003cbr\u003e\u003cbr\u003eThe MVK Polyclonal Antibody is supplied as a liquid formulation in phosphate-buffered saline (PBS) with 0.02% sodium azide as a preservative. It is available in various sizes to meet the needs of different applications. This antibody is suitable for use in both research and diagnostic settings, providing a valuable tool for studying the role of MVK protein in various biological processes and diseases.\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"100ul \/ Rabbit \/ Primary antibody","offer_id":47542345433368,"sku":"BT-AP05666","price":275.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/BT_Lab_5f391e26-c374-4bf1-b4a7-250c136a6a9b.png?v=1705629701","url":"https:\/\/danabiosci.com\/products\/new-product-569341","provider":"Dana Bioscience","version":"1.0","type":"link"}