{"product_id":"new-product-569333","title":"Mucin 1 Polyclonal Antibody","description":"\u003cp\u003eMUC1 encodes a membrane-bound protein that is a member of the mucin family. Mucins are O-glycosylated proteins that play an essential role in forming protective mucous barriers on epithelial surfaces. These proteins also play a role in intracellular signaling. This protein is expressed on the apical surface of epithelial cells that line the mucosal surfaces of many different tissues including lung, breast stomach and pancreas. This protein is proteolytically cleaved into alpha and beta subunits that form a heterodimeric complex. The N-terminal alpha subunit functions in cell-adhesion and the C-terminal beta subunit is involved in cell signaling. Overexpression, aberrant intracellular localization, and changes in glycosylation of this protein have been associated with carcinomas. MUC1 is known to contain a highly polymorphic variable number tandem repeats (VNTR) domain. Alternate splicing results in multiple transcript variants.\u003c\/p\u003e\n\u003cp\u003eThe Mucin 1 Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and analysis of Mucin 1 (MUC1) protein expression. MUC1 is a transmembrane glycoprotein that plays a crucial role in cell adhesion, signaling, and protection of epithelial surfaces. This antibody is produced by immunizing animals with a synthetic peptide corresponding to a specific region of the MUC1 protein sequence.\u003cbr\u003e\u003cbr\u003eThe Mucin 1 Polyclonal Antibody exhibits exceptional affinity and selectivity towards MUC1, making it an ideal choice for various applications, including immunohistochemistry, western blotting, and flow cytometry. It has been rigorously tested and validated to ensure consistent and reliable results across different experimental conditions.\u003cbr\u003e\u003cbr\u003eWith its high sensitivity, this antibody enables the detection of even low levels of MUC1 expression, allowing for accurate quantification and analysis. Its polyclonal nature ensures recognition of multiple epitopes, enhancing the chances of successful detection in various sample types.\u003cbr\u003e\u003cbr\u003eThe Mucin 1 Polyclonal Antibody is supplied as a liquid formulation, ready for immediate use. It is provided in a convenient size, allowing for multiple experiments without the need for frequent reordering. The antibody is stored at the recommended temperature to maintain its stability and functionality.\u003cbr\u003e\u003cbr\u003eIn summary, the Mucin 1 Polyclonal Antibody is a reliable and efficient tool for the detection and analysis of MUC1 protein expression. Its high specificity, sensitivity, and versatility make it an invaluable asset for researchers and scientists working in the fields of cancer biology, immunology, and cell signaling.\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"100ul \/ Rabbit \/ Primary antibody","offer_id":47542327836952,"sku":"BT-AP05657","price":275.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/BT_Lab_af7b21e1-3f74-4b39-a706-09a5f02f5d4b.png?v=1705629643","url":"https:\/\/danabiosci.com\/products\/new-product-569333","provider":"Dana Bioscience","version":"1.0","type":"link"}