{"product_id":"new-product-569315","title":"MSH2 Polyclonal Antibody","description":"\u003cp\u003eMSH2 is frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). When cloned, it was discovered to be a human homolog of the E.coli mismatch repair gene mutS, consistent with the characteristic alterations in microsatellite sequences (RER+ phenotype) found in HNPCC. Two transcript variants encoding different isoforms have been found for this gene.\u003c\/p\u003e\n\u003cp\u003eThe MSH2 Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and analysis of MSH2 protein expression in various biological samples. This antibody is produced using advanced immunization techniques, ensuring high affinity and specificity towards the target protein.\u003cbr\u003e\u003cbr\u003eThe MSH2 protein plays a crucial role in DNA mismatch repair, a process essential for maintaining genomic stability. Dysregulation or mutations in the MSH2 gene have been associated with various hereditary non-polyposis colorectal cancer syndromes and other cancers. Therefore, accurate detection and quantification of MSH2 protein expression are of utmost importance in both research and clinical settings.\u003cbr\u003e\u003cbr\u003eThis polyclonal antibody exhibits exceptional performance in various applications, including Western blotting, immunohistochemistry, and immunofluorescence. It has been rigorously validated to provide reliable and reproducible results, ensuring the utmost confidence in experimental outcomes.\u003cbr\u003e\u003cbr\u003eThe MSH2 Polyclonal Antibody is supplied in a convenient and ready-to-use format, allowing for easy integration into laboratory workflows. It is provided in a liquid formulation, eliminating the need for time-consuming reconstitution steps. Additionally, it is available in different sizes to accommodate various experimental needs.\u003cbr\u003e\u003cbr\u003eWith its exceptional sensitivity, specificity, and reliability, the MSH2 Polyclonal Antibody is an indispensable tool for researchers and clinicians involved in the study of DNA mismatch repair and related diseases. Trust in this high-quality antibody to deliver accurate and precise results, advancing scientific understanding and potentially contributing to the development of novel therapeutic strategies.\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"100ul \/ Rabbit \/ Primary antibody","offer_id":47542288646424,"sku":"BT-AP05622","price":275.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/BT_Lab_dab30e8e-9a15-4df0-9340-9a3f3c914332.png?v=1705629541","url":"https:\/\/danabiosci.com\/products\/new-product-569315","provider":"Dana Bioscience","version":"1.0","type":"link"}