{"product_id":"new-product-569205","title":"MMP-13 Polyclonal Antibody","description":"\u003cp\u003eMMP13 encodes a member of the peptidase M10 family of matrix metalloproteinases (MMPs). Collagenase 3 in this family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. The encoded preproprotein is proteolytically processed to generate the mature protease. This protease cleaves type II collagen more efficiently than types I and III. It may be involved in articular cartilage turnover and cartilage pathophysiology associated with osteoarthritis. Mutations in this gene are associated with metaphyseal anadysplasia. This gene is part of a cluster of MMP genes on chromosome 11.\u003c\/p\u003e\n\u003cp\u003eThe MMP-13 Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and quantification of matrix metalloproteinase-13 (MMP-13) in various biological samples. This antibody is produced using advanced immunization techniques, ensuring high affinity and specificity towards MMP-13.\u003cbr\u003e\u003cbr\u003eMatrix metalloproteinase-13 is a key enzyme involved in the degradation of extracellular matrix components, playing a crucial role in tissue remodeling and repair processes. Dysregulation of MMP-13 has been implicated in various pathological conditions, including cancer, arthritis, and cardiovascular diseases. Therefore, accurate measurement of MMP-13 levels is of utmost importance in understanding disease progression and developing targeted therapeutic interventions.\u003cbr\u003e\u003cbr\u003eThe MMP-13 Polyclonal Antibody exhibits exceptional performance in various immunoassays, including Western blotting, immunohistochemistry, and enzyme-linked immunosorbent assays (ELISA). It recognizes both the pro and active forms of MMP-13, enabling comprehensive analysis of its expression and activity. This antibody demonstrates minimal cross-reactivity with other MMP family members, ensuring reliable and specific results.\u003cbr\u003e\u003cbr\u003eWith its high sensitivity and specificity, the MMP-13 Polyclonal Antibody is an invaluable tool for researchers and clinicians involved in studying MMP-13 biology and its implications in disease. Its superior performance and consistent results make it an ideal choice for a wide range of applications, including basic research, drug discovery, and diagnostic development.\u003cbr\u003e\u003cbr\u003eThe MMP-13 Polyclonal Antibody is supplied in a convenient and ready-to-use format, ensuring ease of use and reproducibility. It is available in various sizes to accommodate different experimental needs. Each batch of antibody undergoes rigorous quality control testing to ensure optimal performance and reliability.\u003cbr\u003e\u003cbr\u003eIn summary, the MMP-13 Polyclonal Antibody is a highly specific and sensitive tool that enables accurate detection and quantification of MMP-13. Its exceptional performance, reliability, and versatility make it an indispensable asset for researchers and clinicians working in the field of MMP-13 biology and related diseases.\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"100ul \/ Rabbit \/ Primary antibody","offer_id":47542224224536,"sku":"BT-AP05477","price":275.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/BT_Lab_bd221e9f-9808-4175-972f-c02103cac748.png?v=1705628971","url":"https:\/\/danabiosci.com\/products\/new-product-569205","provider":"Dana Bioscience","version":"1.0","type":"link"}