{"product_id":"new-product-568977","title":"LRP3 Polyclonal Antibody","description":"\u003cp\u003eNLRP3, also known as NALP3, CIAS1, PYPAF or Cryopyrin, is a cytosolic ~120 kDa member of the NLRP family of proteins expressed in leukocytes, especially neutrophils. As a component of the inflammasome, NLRP3 activates caspases 1 and 5. Defects in NLRP3 may cause FCAS1, CINCA, or Muckle-Wells autoinflammatory syndromes. Mouse NLRP3 contains an N-terminal Pyrin domain (aa 1-91) followed by a Nacht region (aa 216-532), and seven LRRs (aa 739-988). Within the sequence used as an immunogen, mouse NLRP3 shares 78% and 93% aa identity with human and rat NLRP3, respectively. Alternate splicing of mouse NLRP3 generates additional isoforms that lack either LRR2 and 3, LRR 6 and 7, or LRR4-9.\u003c\/p\u003e\n\u003cp\u003eThe LRP3 Polyclonal Antibody is a highly specific and sensitive tool for the detection and analysis of LRP3 protein expression in various biological samples. This antibody has been rigorously validated and exhibits exceptional performance in a wide range of applications, including Western blotting, immunohistochemistry, and immunofluorescence.\u003cbr\u003e\u003cbr\u003eThe LRP3 Polyclonal Antibody is produced using state-of-the-art techniques, ensuring high purity and batch-to-batch consistency. It has been extensively characterized to ensure specificity towards LRP3, minimizing the risk of cross-reactivity with other proteins. This antibody recognizes both the full-length LRP3 protein and its various isoforms, making it a versatile tool for studying LRP3 biology.\u003cbr\u003e\u003cbr\u003eWith its high sensitivity, the LRP3 Polyclonal Antibody allows for the detection of low-abundance LRP3 protein levels, enabling researchers to accurately quantify its expression in different tissues and cell types. Its exceptional signal-to-noise ratio ensures reliable and reproducible results, even in challenging experimental conditions.\u003cbr\u003e\u003cbr\u003eThe LRP3 Polyclonal Antibody is supplied as a liquid formulation, ready for immediate use. It is provided in a convenient size, allowing for multiple experiments without the need for frequent reordering. The antibody is stable and can be stored at -20°C, ensuring long-term usability.\u003cbr\u003e\u003cbr\u003eIn summary, the LRP3 Polyclonal Antibody is a highly reliable and specific tool for the detection and analysis of LRP3 protein expression. Its exceptional performance, versatility, and ease of use make it an invaluable asset for researchers studying LRP3 biology in various fields, including cancer research, neurobiology, and cardiovascular research.\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"100ul \/ Rabbit \/ Primary antibody","offer_id":47542072803608,"sku":"BT-AP05078","price":275.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/BT_Lab_2e296304-dbf8-4f4f-afd9-5d89f81c2545.png?v=1705627741","url":"https:\/\/danabiosci.com\/products\/new-product-568977","provider":"Dana Bioscience","version":"1.0","type":"link"}