{"product_id":"new-product-568976","title":"LRP11 Polyclonal Antibody","description":"\u003cp\u003eMembers of the LDL receptor gene family, including LDLR (low density lipoprotein receptor), LRP1 (low density lipoprotein related protein), Megalin (also designated GP330), VLDLR (very low density lipoprotein receptor) and ApoER2 are characterized by a cluster of cysteine-rich class A repeats, epidermal growth factor (EGF)-like repeats, YWTD repeats and an O-linked sugar domain. LRP11 (low density lipoprotein receptor-related protein 11), also known as MANSC3, is a 500 amino acid single-pass type I membrane protein that exists as two alternatively spliced isoforms. LRP11 is encoded by a gene located on human chromosome 6q25. Chromosome 6 contains 170 million base pairs and comprises nearly 6% of the human genome. Deletion of a portion of the q arm of chromosome 6 is associated with early onset intestinal cancer, suggesting the presence of a cancer susceptibility locus. Additionally, Porphyria cutanea tarda, Parkinson's disease, Stickler syndrome and a susceptibility to bipolar disorder are all associated with genes that map to chromosome 6.\u003c\/p\u003e\n\u003cp\u003eThe LRP11 Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and analysis of LRP11 protein expression in various biological samples. This antibody is produced using state-of-the-art technology and rigorous quality control measures to ensure optimal performance and reliability.\u003cbr\u003e\u003cbr\u003eLRP11, also known as low-density lipoprotein receptor-related protein 11, is a cell surface receptor that plays a crucial role in various cellular processes, including endocytosis, signal transduction, and cell adhesion. Dysregulation of LRP11 has been implicated in several diseases, making it an important target for research and diagnostic purposes.\u003cbr\u003e\u003cbr\u003eThe LRP11 Polyclonal Antibody exhibits exceptional specificity, binding exclusively to the LRP11 protein without cross-reactivity to other related proteins. This high specificity allows for accurate and reliable detection of LRP11 expression levels in a variety of sample types, including cell lysates, tissue homogenates, and biological fluids.\u003cbr\u003e\u003cbr\u003eFurthermore, this antibody demonstrates excellent sensitivity, enabling the detection of low levels of LRP11 protein expression. Its superior sensitivity ensures reliable results even with limited sample quantities, making it an ideal choice for studies requiring minimal sample consumption.\u003cbr\u003e\u003cbr\u003eThe LRP11 Polyclonal Antibody is supplied as a liquid formulation, ready for immediate use. It is provided in a convenient size and concentration, allowing for easy customization and optimization of experimental conditions. Additionally, this antibody is compatible with various detection methods, including Western blotting, immunohistochemistry, and immunofluorescence, providing flexibility for different research applications.\u003cbr\u003e\u003cbr\u003eIn summary, the LRP11 Polyclonal Antibody is a highly specific, sensitive, and reliable tool for the detection and analysis of LRP11 protein expression. Its exceptional performance characteristics, compatibility with multiple detection methods, and ease of use make it an invaluable asset for researchers and clinicians alike in their pursuit of understanding the role of LRP11 in health and disease.\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"100ul \/ Rabbit \/ Primary antibody","offer_id":47542072738072,"sku":"BT-AP05074","price":275.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/BT_Lab_0f59a8a1-9103-42b7-857d-bae1d766aba4.png?v=1705627737","url":"https:\/\/danabiosci.com\/products\/new-product-568976","provider":"Dana Bioscience","version":"1.0","type":"link"}