{"product_id":"new-product-568951","title":"LIR-1 Polyclonal Antibody","description":"\u003cp\u003eLILRB1 is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13. The leukocyte immunoglobulin like receptor B1 belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). The receptor is expressed on immune cells where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response. It is thought to control inflammatory responses and cytotoxicity to help focus the immune response and limit autoreactivity. Multiple transcript variants encoding different isoforms have been found for this gene.\u003c\/p\u003e\n\u003cp\u003eThe LIR-1 Polyclonal Antibody is a highly specific and sensitive immunological tool designed for the detection and analysis of LIR-1 protein expression. This antibody is produced using advanced techniques, ensuring its high affinity and specificity towards LIR-1. \u003cbr\u003e\u003cbr\u003eLIR-1, also known as leukocyte immunoglobulin-like receptor 1, is a cell surface receptor that plays a crucial role in regulating immune responses. It is primarily expressed on myeloid cells, including monocytes, macrophages, and dendritic cells. LIR-1 has been implicated in various immune-related processes, such as immune tolerance, inflammation, and immune cell activation.\u003cbr\u003e\u003cbr\u003eThe LIR-1 Polyclonal Antibody is validated for multiple applications, including Western blotting, immunohistochemistry, and flow cytometry. It exhibits excellent performance in detecting LIR-1 protein expression in various sample types, such as cell lysates, tissue sections, and isolated immune cells. \u003cbr\u003e\u003cbr\u003eWith its high sensitivity and specificity, this antibody enables researchers to accurately quantify and analyze LIR-1 expression levels in different experimental settings. Its reliable performance ensures reproducible and robust results, facilitating further investigations into the functional role of LIR-1 in immune regulation.\u003cbr\u003e\u003cbr\u003eThe LIR-1 Polyclonal Antibody is supplied in a convenient format, allowing for easy handling and storage. It is provided in a liquid formulation, eliminating the need for reconstitution and ensuring immediate usability. Each batch of the antibody undergoes rigorous quality control procedures to guarantee consistent performance and reliability.\u003cbr\u003e\u003cbr\u003eIn summary, the LIR-1 Polyclonal Antibody is a valuable tool for researchers studying immune regulation and related processes. Its high specificity, sensitivity, and versatility make it an essential component in immunological research, enabling precise detection and analysis of LIR-1 protein expression.\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"100ul \/ Rabbit \/ Primary antibody","offer_id":47542069788952,"sku":"BT-AP05029","price":275.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/BT_Lab_ce9d7769-7383-49c1-8777-8b202972d2b9.png?v=1705627612","url":"https:\/\/danabiosci.com\/products\/new-product-568951","provider":"Dana Bioscience","version":"1.0","type":"link"}