{"product_id":"new-product-568723","title":"Integrin Beta4 Polyclonal Antibody","description":"\u003cp\u003eIntegrins are heterodimers comprised of alpha and beta subunits, that are noncovalently associated transmembrane glycoprotein receptors. Different combinations of alpha and beta polypeptides form complexes that vary in their ligand-binding specificities. Integrins mediate cell-matrix or cell-cell adhesion, and transduced signals that regulate gene expression and cell growth. ITGB4 encodes Integrin beta-4, a receptor for the laminins. This subunit tends to associate with alpha 6 subunit and is likely to play a pivotal role in the biology of invasive carcinoma. Mutations in this gene are associated with epidermolysis bullosa with pyloric atresia. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eThe Integrin Beta4 Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and analysis of Integrin Beta4 protein expression in various biological samples. This antibody is produced using advanced immunization techniques and exhibits exceptional affinity and selectivity towards Integrin Beta4.\u003c\/span\u003e\u003cbr\u003e\u003cbr\u003e\u003cspan\u003eIntegrin Beta4 is a transmembrane protein that plays a crucial role in cell adhesion and migration processes. It is primarily expressed in epithelial cells and is involved in the formation and maintenance of epithelial tissues. Dysregulation of Integrin Beta4 expression has been implicated in various pathological conditions, including cancer metastasis and tissue fibrosis.\u003c\/span\u003e\u003cbr\u003e\u003cbr\u003e\u003cspan\u003eThe Integrin Beta4 Polyclonal Antibody is validated for use in various applications, including Western blotting, immunohistochemistry, and immunofluorescence. It has been rigorously tested to ensure high specificity and minimal cross-reactivity with other related proteins. This antibody exhibits excellent sensitivity, allowing for the detection of low levels of Integrin Beta4 expression in even the most challenging samples.\u003c\/span\u003e\u003cbr\u003e\u003cbr\u003e\u003cspan\u003eWith its superior performance characteristics, the Integrin Beta4 Polyclonal Antibody is an indispensable tool for researchers and clinicians studying the role of Integrin Beta4 in various biological processes and disease states. Its reliable and reproducible results make it an ideal choice for both basic research and clinical applications.\u003c\/span\u003e\u003cbr\u003e\u003cbr\u003e\u003cspan\u003eOrder your Integrin Beta4 Polyclonal Antibody today and unlock new insights into the intricate mechanisms underlying cell adhesion and migration.\u003c\/span\u003e\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"100ul \/ Rabbit \/ Primary antibody","offer_id":47541899460888,"sku":"BT-AP04590","price":275.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/BT_Lab_e8ff524f-6a52-4be2-ab36-fc8d7d4c2912.png?v=1705626325","url":"https:\/\/danabiosci.com\/products\/new-product-568723","provider":"Dana Bioscience","version":"1.0","type":"link"}