{"product_id":"new-product-568629","title":"IL-17R Alpha Polyclonal Antibody","description":"\u003cp\u003eIL17RC encodes a single-pass type I membrane protein that shares similarity with the interleukin-17 receptor (IL-17RA). Unlike IL-17RA, which is predominantly expressed in hemopoietic cells, and binds with high affinity to only IL-17A, Interleukin-17 receptor C is expressed in nonhemopoietic tissues, and binds both IL-17A and IL-17F with similar affinities. The proinflammatory cytokines, IL-17A and IL-17F, have been implicated in the progression of inflammatory and autoimmune diseases. Multiple alternatively spliced transcript variants encoding different isoforms have been detected for this gene, and it has been proposed that soluble, secreted proteins lacking transmembrane and intracellular domains may function as extracellular antagonists to cytokine signaling.\u003c\/p\u003e\n\u003cp\u003eThe IL-17R Alpha Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and quantification of IL-17R Alpha protein in various biological samples. This antibody is produced using advanced recombinant DNA technology, ensuring high purity and batch-to-batch consistency.\u003cbr\u003e\u003cbr\u003eIL-17R Alpha is a crucial receptor involved in the signaling pathway of interleukin-17 (IL-17), a pro-inflammatory cytokine. It plays a significant role in the regulation of immune responses and the development of various autoimmune and inflammatory diseases. The IL-17R Alpha Polyclonal Antibody has been extensively validated for its specificity and sensitivity in various experimental settings, including Western blotting, immunohistochemistry, and flow cytometry.\u003cbr\u003e\u003cbr\u003eWith its exceptional performance, this antibody enables researchers to accurately analyze the expression and localization of IL-17R Alpha in different tissues and cell types. Its high affinity and low background ensure reliable and reproducible results, making it an ideal choice for both basic research and clinical applications.\u003cbr\u003e\u003cbr\u003eThe IL-17R Alpha Polyclonal Antibody is supplied as a liquid formulation, ready to use for various experimental techniques. It is provided in a convenient size and format, allowing for easy handling and storage. Each batch is meticulously quality-controlled to ensure consistent performance and reliability.\u003cbr\u003e\u003cbr\u003eIn summary, the IL-17R Alpha Polyclonal Antibody is a valuable tool for researchers studying the role of IL-17R Alpha in immune responses and inflammatory diseases. Its exceptional specificity, sensitivity, and reliability make it an indispensable asset in the field of immunology and biomedical research.\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"100ul \/ Rabbit \/ Primary antibody","offer_id":47541860532504,"sku":"BT-AP04455","price":275.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/BT_Lab_e2072110-20dd-4237-8622-1d4d9e6ad4e8.png?v=1705625793","url":"https:\/\/danabiosci.com\/products\/new-product-568629","provider":"Dana Bioscience","version":"1.0","type":"link"}