IL-11R Alpha Polyclonal Antibody

Interleukin 11 is a stromal cell-derived cytokine that belongs to a family of pleiotropic and redundant cytokines that use the gp130 transducing subunit in their high affinity receptors. IL11RA encodes the Interleukin-11 receptor subunit alpha, which is a member of the hematopoietic cytokine receptor family. Interleukin-11 receptor subunit alpha is very similar to ciliary neurotrophic factor, since both contain an extracellular region with a 2-domain structure composed of an immunoglobulin-like domain and a cytokine receptor-like domain. Multiple alternatively spliced transcript variants have been found for this gene.

The IL-11R Alpha Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and quantification of IL-11R Alpha protein in various biological samples. This antibody has been extensively validated for its superior performance in immunohistochemistry (IHC), immunofluorescence (IF), and western blotting (WB) applications.

IL-11R Alpha, also known as Interleukin-11 receptor subunit alpha, is a transmembrane protein that plays a crucial role in the signaling pathway of IL-11, a cytokine involved in various physiological processes such as hematopoiesis, bone metabolism, and immune response. The IL-11R Alpha Polyclonal Antibody specifically recognizes the extracellular domain of IL-11R Alpha, enabling precise and accurate detection of this protein.

This antibody exhibits exceptional sensitivity and specificity, ensuring reliable and reproducible results. It has been rigorously tested against a wide range of cell lines and tissues, demonstrating its robust performance in various experimental conditions. The IL-11R Alpha Polyclonal Antibody exhibits minimal cross-reactivity with other related proteins, further enhancing its specificity.

The IL-11R Alpha Polyclonal Antibody is supplied as a purified and lyophilized formulation, ensuring long-term stability and ease of use. It can be reconstituted in a suitable buffer for immediate application or aliquoted for storage at -20°C. This antibody is compatible with a variety of detection systems and can be used in combination with other antibodies for multiplex analysis.

In summary, the IL-11R Alpha Polyclonal Antibody is a reliable and versatile tool for the detection and quantification of IL-11R Alpha protein. Its exceptional sensitivity, specificity, and robust performance make it an ideal choice for researchers studying the role of IL-11R Alpha in various biological processes.