{"product_id":"new-product-568444","title":"HLA-DOBeta Polyclonal Antibody","description":"\u003cp\u003eHLA-DOB belongs to the HLA class II beta chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DOA) and a beta chain (DOB), both anchored in the membrane. It is located in intracellular vesicles. DO suppresses peptide loading of MHC class II molecules by inhibiting HLA-DM. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The beta chain is approximately 26-28 kDa and its gene contains 6 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and exon 5 encodes the cytoplasmic tail.\u003c\/p\u003e\n\u003cp\u003eThe HLA-DOBeta Polyclonal Antibody is a highly specific and reliable tool designed for the detection and analysis of HLA-DOBeta protein expression. This antibody is produced through a rigorous process, ensuring its high affinity and sensitivity towards the target protein. \u003cbr\u003e\u003cbr\u003eWith its polyclonal nature, this antibody exhibits a broad reactivity, making it suitable for various applications, including Western blotting, immunohistochemistry, and flow cytometry. Its versatility allows for the examination of HLA-DOBeta expression in different sample types, such as cell lysates, tissue sections, and whole blood.\u003cbr\u003e\u003cbr\u003eThe HLA-DOBeta Polyclonal Antibody offers exceptional performance, delivering accurate and reproducible results. Its superior specificity ensures minimal cross-reactivity with other proteins, guaranteeing reliable and precise data interpretation. \u003cbr\u003e\u003cbr\u003eFurthermore, this antibody is manufactured under strict quality control standards, ensuring batch-to-batch consistency and reliability. Its long shelf life and stability make it an ideal choice for long-term experiments and storage.\u003cbr\u003e\u003cbr\u003eIn summary, the HLA-DOBeta Polyclonal Antibody is a valuable tool for researchers and scientists in the field of immunology. Its high specificity, broad reactivity, and reliable performance make it an essential component for the investigation of HLA-DOBeta protein expression and its role in various biological processes.\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"100ul \/ Rabbit \/ Primary antibody","offer_id":47541788115224,"sku":"BT-AP04129","price":275.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/BT_Lab_41c2868f-0968-401c-b96a-3d3f916f7943.png?v=1705624771","url":"https:\/\/danabiosci.com\/products\/new-product-568444","provider":"Dana Bioscience","version":"1.0","type":"link"}