{"product_id":"new-product-568435","title":"Histone H4 Polyclonal Antibody","description":"\u003cp\u003eHistones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. This structure consists of approximately 146 bp of DNA wrapped around a nucleosome, an octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H3 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6p22-p21.3.\u003c\/p\u003e\n\u003cp\u003eThe Histone H4 Polyclonal Antibody is a highly specific and sensitive tool for the detection and analysis of histone H4 protein. This antibody is produced using a polyclonal approach, ensuring a diverse range of epitope recognition and enhanced sensitivity. It has been extensively validated for various applications, including Western blotting, immunohistochemistry, and immunofluorescence. \u003cbr\u003e\u003cbr\u003eThe Histone H4 Polyclonal Antibody exhibits exceptional specificity, binding exclusively to the histone H4 protein without cross-reactivity to other histone variants. This specificity allows for accurate and reliable detection of histone H4 in various biological samples. \u003cbr\u003e\u003cbr\u003eWith its high sensitivity, the Histone H4 Polyclonal Antibody enables the detection of low abundance histone H4 protein, making it an ideal choice for studies requiring precise quantification. Its robust performance ensures consistent and reproducible results, even with limited sample amounts. \u003cbr\u003e\u003cbr\u003eThe Histone H4 Polyclonal Antibody is supplied as a ready-to-use solution, eliminating the need for time-consuming antibody preparation. Its optimized formulation ensures stability and long shelf life, allowing for convenient storage and repeated use. \u003cbr\u003e\u003cbr\u003eIn summary, the Histone H4 Polyclonal Antibody is a reliable and versatile tool for the detection and analysis of histone H4 protein. Its exceptional specificity, high sensitivity, and ease of use make it an essential component for researchers in the field of epigenetics and chromatin biology.\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"100ul \/ Rabbit \/ Primary antibody","offer_id":47541783331096,"sku":"BT-AP04116","price":275.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/BT_Lab_ec2d2194-6617-469a-9f7a-7ff3602a2de1.png?v=1705624709","url":"https:\/\/danabiosci.com\/products\/new-product-568435","provider":"Dana Bioscience","version":"1.0","type":"link"}