{"product_id":"new-product-568433","title":"Histone H4 (Tri Methyl Lys79) Polyclonal Antibody","description":"\u003cp\u003eHistones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. HIST4H4 is intronless and encodes a replication-dependent histone that is a member of the histone H4 family. Transcripts from HIST4H4 lack polyA tails; instead, they contain a palindromic termination element.\u003c\/p\u003e\n\u003cp\u003eThe Histone H4 (Tri Methyl Lys79) Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and analysis of histone H4 protein modifications. This antibody is produced using advanced techniques to ensure high affinity and specificity towards the tri methyl lysine 79 modification on histone H4. \u003cbr\u003e\u003cbr\u003eHistone H4 is a crucial component of chromatin structure and plays a vital role in gene regulation and DNA packaging. The tri methyl lysine 79 modification on histone H4 has been implicated in various biological processes, including transcriptional activation, DNA repair, and cell cycle regulation. \u003cbr\u003e\u003cbr\u003eThis polyclonal antibody is rigorously validated for its performance in various applications, including Western blotting, immunoprecipitation, and immunofluorescence. It exhibits minimal cross-reactivity with other histone modifications, ensuring accurate and reliable results. \u003cbr\u003e\u003cbr\u003eWith its high sensitivity and specificity, the Histone H4 (Tri Methyl Lys79) Polyclonal Antibody is an indispensable tool for researchers studying epigenetics, chromatin biology, and gene regulation. Its superior performance and consistent results make it an ideal choice for both basic research and clinical applications.\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"100ul \/ Rabbit \/ Primary antibody","offer_id":47541783265560,"sku":"BT-AP04114","price":275.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/BT_Lab_8c5ac55f-6654-4957-9b11-e2ca0d18bd5e.png?v=1705624699","url":"https:\/\/danabiosci.com\/products\/new-product-568433","provider":"Dana Bioscience","version":"1.0","type":"link"}