{"product_id":"new-product-568424","title":"Histone H4 (Acetyl Lys8) Polyclonal Antibody","description":"\u003cp\u003eHistones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. HIST4H4 is intronless and encodes a replication-dependent histone that is a member of the histone H4 family. Transcripts from HIST4H4 lack polyA tails; instead, they contain a palindromic termination element.\u003c\/p\u003e\n\u003cp\u003eThe Histone H4 (Acetyl Lys8) Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and quantification of Histone H4 protein acetylated at Lysine 8. This antibody is produced through a rigorous process of immunization and purification, ensuring high affinity and specificity towards the target antigen.\u003cbr\u003e\u003cbr\u003eHistone H4 is a core histone protein that plays a crucial role in chromatin structure and gene regulation. Acetylation of Lysine 8 on Histone H4 has been implicated in various biological processes, including transcriptional activation and DNA repair. Therefore, the detection and analysis of Histone H4 acetylated at Lysine 8 is of great importance in understanding the epigenetic mechanisms underlying gene expression and cellular processes.\u003cbr\u003e\u003cbr\u003eThe Histone H4 (Acetyl Lys8) Polyclonal Antibody exhibits exceptional performance in a wide range of applications, including Western blotting, immunohistochemistry, and chromatin immunoprecipitation. It has been validated for use in various species, including human, mouse, and rat, ensuring its versatility and applicability in diverse research settings.\u003cbr\u003e\u003cbr\u003eThis antibody is supplied as a liquid formulation, allowing for easy handling and storage. It is provided in a convenient size, ensuring cost-effectiveness and minimizing waste. Each batch of the Histone H4 (Acetyl Lys8) Polyclonal Antibody undergoes rigorous quality control testing to ensure consistent and reliable results.\u003cbr\u003e\u003cbr\u003eIn summary, the Histone H4 (Acetyl Lys8) Polyclonal Antibody is a valuable tool for researchers studying epigenetics and chromatin biology. Its high specificity, sensitivity, and versatility make it an ideal choice for the detection and quantification of Histone H4 protein acetylated at Lysine 8, enabling a deeper understanding of the intricate mechanisms governing gene expression and cellular processes.\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"100ul \/ Rabbit \/ Primary antibody","offer_id":47541780316440,"sku":"BT-AP04105","price":275.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/BT_Lab_efa69fed-4e51-45c1-9827-d9829818ba48.png?v=1705624658","url":"https:\/\/danabiosci.com\/products\/new-product-568424","provider":"Dana Bioscience","version":"1.0","type":"link"}