{"product_id":"new-product-568423","title":"Histone H4 (Acetyl Lys5) Polyclonal Antibody","description":"\u003cp\u003eHistones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. HIST4H4 is intronless and encodes a replication-dependent histone that is a member of the histone H4 family. Transcripts from HIST4H4 lack polyA tails; instead, they contain a palindromic termination element.\u003c\/p\u003e\n\u003cp\u003eThe Histone H4 (Acetyl Lys5) Polyclonal Antibody is a highly specific and sensitive tool for the detection and analysis of acetylated lysine 5 on histone H4. This antibody is produced using advanced techniques and high-quality materials to ensure optimal performance and reliability.\u003cbr\u003e\u003cbr\u003eHistone H4 is a core histone protein that plays a crucial role in chromatin structure and gene regulation. Acetylation of lysine residues on histone H4 is an important post-translational modification that is associated with transcriptional activation and chromatin remodeling. The Histone H4 (Acetyl Lys5) Polyclonal Antibody specifically recognizes and binds to acetylated lysine 5 on histone H4, allowing for the precise identification and quantification of this modification.\u003cbr\u003e\u003cbr\u003eThis antibody has been extensively validated for various applications, including Western blotting, immunohistochemistry, and chromatin immunoprecipitation. It exhibits high specificity and sensitivity, enabling accurate detection of acetylated lysine 5 on histone H4 in a wide range of samples.\u003cbr\u003e\u003cbr\u003eThe Histone H4 (Acetyl Lys5) Polyclonal Antibody is supplied as a liquid formulation in a convenient size, allowing for easy handling and storage. It is provided in a ready-to-use format, eliminating the need for time-consuming and complex preparation steps.\u003cbr\u003e\u003cbr\u003eWith its exceptional performance and reliability, the Histone H4 (Acetyl Lys5) Polyclonal Antibody is an indispensable tool for researchers studying epigenetics, chromatin biology, and gene regulation. Its high specificity and sensitivity make it an ideal choice for accurate and precise analysis of acetylated lysine 5 on histone H4.\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"100ul \/ Rabbit \/ Primary antibody","offer_id":47541780152600,"sku":"BT-AP04104","price":275.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/BT_Lab_79879ff7-9a3c-4fce-83ba-4ba2848a4c7a.png?v=1705624654","url":"https:\/\/danabiosci.com\/products\/new-product-568423","provider":"Dana Bioscience","version":"1.0","type":"link"}