{"product_id":"new-product-568407","title":"Histone H3 (Tri Methyl Lys79) Polyclonal Antibody","description":"\u003cp\u003eHistones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. This structure consists of approximately 146 bp of DNA wrapped around a nucleosome, an octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. HIST1H3A (histone cluster 1 H3 family member a) is intronless and encodes a replication-dependent histone that is a member of the histone H3 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. HIST1H3A is found in the large histone gene cluster on chromosome 6p22-p21.3.\u003c\/p\u003e\n\u003cp\u003eThe Histone H3 (Tri Methyl Lys79) Polyclonal Antibody is a highly specific and sensitive tool for the detection and analysis of histone H3 protein modifications. This antibody is designed to specifically recognize and bind to the tri-methylated lysine 79 residue on histone H3, allowing for the precise identification and quantification of this specific modification.\u003cbr\u003e\u003cbr\u003eThe Histone H3 (Tri Methyl Lys79) Polyclonal Antibody has been extensively validated for use in various applications, including Western blotting, immunohistochemistry, and chromatin immunoprecipitation. Its high affinity and specificity ensure reliable and accurate results, making it an essential tool for researchers studying epigenetic modifications and their role in gene expression and cellular processes.\u003cbr\u003e\u003cbr\u003eThis antibody is produced using a polyclonal approach, resulting in a diverse population of antibodies that recognize different epitopes on the target protein. This broad recognition profile enhances the versatility and utility of the antibody, allowing for the detection of various isoforms and post-translational modifications of histone H3.\u003cbr\u003e\u003cbr\u003eThe Histone H3 (Tri Methyl Lys79) Polyclonal Antibody is manufactured using state-of-the-art techniques and undergoes rigorous quality control to ensure batch-to-batch consistency and reproducibility. It is supplied as a liquid formulation, ready for immediate use, and is available in various sizes to meet the specific needs of different experimental setups.\u003cbr\u003e\u003cbr\u003eIn summary, the Histone H3 (Tri Methyl Lys79) Polyclonal Antibody is a reliable and highly specific tool for the detection and analysis of histone H3 protein modifications. Its versatility, sensitivity, and accuracy make it an indispensable asset for researchers in the field of epigenetics and chromatin biology.\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"100ul \/ Rabbit \/ Primary antibody","offer_id":47541776449816,"sku":"BT-AP04076","price":275.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/BT_Lab_f2e3f481-c3e4-4987-ad5a-a6508bf0060e.png?v=1705624584","url":"https:\/\/danabiosci.com\/products\/new-product-568407","provider":"Dana Bioscience","version":"1.0","type":"link"}