{"product_id":"new-product-568397","title":"Histone H3 (Mono Methyl Lys37) Polyclonal Antibody","description":"\u003cp\u003eHistones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. This structure consists of approximately 146 bp of DNA wrapped around a nucleosome, an octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. HIST1H3A is intronless and encodes a replication-dependent histone that is a member of the histone H3 family. Transcripts from HIST1H3A lack polyA tails; instead, they contain a palindromic termination element. HIST1H3A is found in the large histone gene cluster on chromosome 6p22-p21.3.\u003c\/p\u003e\n\u003cp\u003eThe Histone H3 (Mono Methyl Lys37) Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and analysis of histone H3 mono-methylated at lysine 37. This antibody is produced using high-quality polyclonal antibodies that have been carefully selected and validated for their specificity and performance.\u003cbr\u003e\u003cbr\u003eHistone H3 is a crucial protein involved in the packaging and organization of DNA within the nucleus. Post-translational modifications of histone H3, such as methylation, play a critical role in regulating gene expression and chromatin structure. The mono-methylation of lysine 37 on histone H3 has been implicated in various biological processes, including transcriptional regulation, DNA repair, and cell cycle progression.\u003cbr\u003e\u003cbr\u003eThe Histone H3 (Mono Methyl Lys37) Polyclonal Antibody has been rigorously tested and validated for its specificity and sensitivity in various applications, including Western blotting, immunohistochemistry, and chromatin immunoprecipitation (ChIP). It exhibits minimal cross-reactivity with other histone modifications, ensuring accurate and reliable results.\u003cbr\u003e\u003cbr\u003eThis antibody is supplied as a liquid formulation, ready for immediate use. It is provided in a convenient size and concentration, allowing for easy handling and storage. The antibody has been optimized for use in a variety of experimental conditions, ensuring consistent and reproducible results.\u003cbr\u003e\u003cbr\u003eWith its high specificity, sensitivity, and versatility, the Histone H3 (Mono Methyl Lys37) Polyclonal Antibody is an essential tool for researchers studying histone modifications and their role in gene regulation and chromatin dynamics. Its reliable performance and consistent results make it an ideal choice for a wide range of applications in molecular biology, genetics, and epigenetics research.\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"100ul \/ Rabbit \/ Primary antibody","offer_id":47541772288280,"sku":"BT-AP04066","price":275.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/BT_Lab_194b4e67-3d86-4954-9208-a77f542d1b8c.png?v=1705624531","url":"https:\/\/danabiosci.com\/products\/new-product-568397","provider":"Dana Bioscience","version":"1.0","type":"link"}