{"product_id":"new-product-568385","title":"Histone H3 (Di Methyl Lys36) Polyclonal Antibody","description":"\u003cp\u003eHistones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. This structure consists of approximately 146 bp of DNA wrapped around a nucleosome, an octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. HIST1H3A (histone cluster 1 H3 family member a) is intronless and encodes a replication-dependent histone that is a member of the histone H3 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. HIST1H3A is found in the large histone gene cluster on chromosome 6p22-p21.3.\u003c\/p\u003e\n\u003cp\u003eThe Histone H3 (Di Methyl Lys36) Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and analysis of histone H3 protein modifications. This antibody is produced using advanced techniques to ensure high affinity and specificity towards the di methylated lysine 36 residue of histone H3. \u003cbr\u003e\u003cbr\u003eHistone H3 is a crucial component of chromatin structure and plays a vital role in gene regulation and DNA packaging. The di methylation of lysine 36 on histone H3 has been implicated in various biological processes, including transcriptional activation and DNA repair. \u003cbr\u003e\u003cbr\u003eThis polyclonal antibody is rigorously tested and validated to ensure consistent and reliable results. It exhibits minimal cross-reactivity with other histone modifications, ensuring accurate detection and quantification of di methylated lysine 36 on histone H3. \u003cbr\u003e\u003cbr\u003eThe Histone H3 (Di Methyl Lys36) Polyclonal Antibody is suitable for a wide range of applications, including Western blotting, immunoprecipitation, chromatin immunoprecipitation (ChIP), and immunofluorescence. It is compatible with various sample types, including cell lysates, tissue extracts, and purified histones. \u003cbr\u003e\u003cbr\u003eWith its high sensitivity and specificity, this antibody enables researchers to investigate the role of histone H3 di methylation in various biological processes and disease states. It is an essential tool for studying epigenetic modifications and chromatin dynamics. \u003cbr\u003e\u003cbr\u003eOrder the Histone H3 (Di Methyl Lys36) Polyclonal Antibody today and enhance your research capabilities in the field of histone biology and epigenetics.\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"100ul \/ Rabbit \/ Primary antibody","offer_id":47541769208088,"sku":"BT-AP04053","price":275.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/BT_Lab_cb65c9dc-a6fd-4ec9-b289-e13fb7b2b7a6.png?v=1705624484","url":"https:\/\/danabiosci.com\/products\/new-product-568385","provider":"Dana Bioscience","version":"1.0","type":"link"}