{"product_id":"new-product-568381","title":"Histone H3 (Acetyl Lys9) Polyclonal Antibody","description":"\u003cp\u003eHistones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. This structure consists of approximately 146 bp of DNA wrapped around a nucleosome, an octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. HIST1H3A is intronless and encodes a replication-dependent histone that is a member of the histone H3 family. Transcripts from HIST1H3A lack polyA tails; instead, they contain a palindromic termination element. HIST1H3A is found in the large histone gene cluster on chromosome 6p22-p21.3.\u003c\/p\u003e\n\u003cp\u003eThe Histone H3 (Acetyl Lys9) Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and analysis of acetylated Lysine 9 residue on Histone H3. This antibody is produced using a polyclonal approach, ensuring a diverse population of antibodies that recognize the target epitope with high affinity and specificity.\u003cbr\u003e\u003cbr\u003eHistone H3 is a crucial component of chromatin structure and plays a vital role in gene regulation and DNA packaging. Acetylation of Lysine 9 on Histone H3 is known to be associated with transcriptional activation and is an important epigenetic modification involved in various biological processes.\u003cbr\u003e\u003cbr\u003eThe Histone H3 (Acetyl Lys9) Polyclonal Antibody has been rigorously validated for its performance in various applications, including Western blotting, immunohistochemistry, and chromatin immunoprecipitation. It exhibits excellent sensitivity and specificity, enabling accurate and reliable detection of acetylated Lysine 9 on Histone H3 in various biological samples.\u003cbr\u003e\u003cbr\u003eThis antibody is supplied as a liquid formulation, allowing for easy handling and convenient storage. It is provided in a ready-to-use format, eliminating the need for time-consuming and complex preparation steps. The antibody is also available in different sizes to accommodate various experimental needs.\u003cbr\u003e\u003cbr\u003eWith its exceptional performance and versatility, the Histone H3 (Acetyl Lys9) Polyclonal Antibody is an indispensable tool for researchers studying epigenetics, chromatin biology, and gene regulation. Its high specificity and sensitivity make it an ideal choice for investigating the role of acetylated Lysine 9 on Histone H3 in various biological processes and disease states.\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"100ul \/ Rabbit \/ Primary antibody","offer_id":47541767405848,"sku":"BT-AP04047","price":275.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/BT_Lab_764eb543-48dc-4a69-8756-1aaba56bb59d.png?v=1705624458","url":"https:\/\/danabiosci.com\/products\/new-product-568381","provider":"Dana Bioscience","version":"1.0","type":"link"}