{"product_id":"new-product-568378","title":"Histone H3 (Acetyl Lys56) Polyclonal Antibody","description":"\u003cp\u003eHistones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. This structure consists of approximately 146 bp of DNA wrapped around a nucleosome, an octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. HIST1H3A is intronless and encodes a replication-dependent histone that is a member of the histone H3 family. Transcripts from HIST1H3A lack polyA tails; instead, they contain a palindromic termination element. HIST1H3A is found in the large histone gene cluster on chromosome 6p22-p21.3.\u003c\/p\u003e\n\u003cp\u003eThe Histone H3 (Acetyl Lys56) Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and analysis of Histone H3 acetylated at Lysine 56. This antibody is produced using a polyclonal approach, ensuring a high affinity and specificity for the target antigen. \u003cbr\u003e\u003cbr\u003eHistone H3 is a crucial component of chromatin structure and plays a vital role in gene regulation and DNA packaging. Acetylation of Lysine 56 on Histone H3 has been implicated in various biological processes, including DNA repair, replication, and transcriptional regulation. \u003cbr\u003e\u003cbr\u003eThe Histone H3 (Acetyl Lys56) Polyclonal Antibody has been rigorously validated for its performance in various applications, including Western blotting, immunohistochemistry, and immunofluorescence. It exhibits excellent sensitivity and specificity, enabling accurate and reliable detection of Histone H3 acetylated at Lysine 56 in various biological samples. \u003cbr\u003e\u003cbr\u003eThis antibody is supplied as a liquid formulation, allowing for easy handling and convenient storage. It is provided in a ready-to-use format, eliminating the need for time-consuming preparation steps. \u003cbr\u003e\u003cbr\u003eWith its exceptional performance and reliability, the Histone H3 (Acetyl Lys56) Polyclonal Antibody is an indispensable tool for researchers studying epigenetics, chromatin biology, and gene regulation. Its high specificity and sensitivity make it an ideal choice for investigating the role of Histone H3 acetylation in various biological processes.\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"100ul \/ Rabbit \/ Primary antibody","offer_id":47541765538072,"sku":"BT-AP04044","price":275.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/BT_Lab_075195a5-50de-4b2a-bb56-94b65255f248.png?v=1705624433","url":"https:\/\/danabiosci.com\/products\/new-product-568378","provider":"Dana Bioscience","version":"1.0","type":"link"}