{"product_id":"new-product-568373","title":"Histone H3 (Acetyl Lys23) Polyclonal Antibody","description":"\u003cp\u003eHistones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. This structure consists of approximately 146 bp of DNA wrapped around a nucleosome, an octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. HIST1H3A is intronless and encodes a replication-dependent histone that is a member of the histone H3 family. Transcripts from HIST1H3A lack polyA tails; instead, they contain a palindromic termination element. HIST1H3A is found in the large histone gene cluster on chromosome 6p22-p21.3.\u003c\/p\u003e\n\u003cp\u003eThe Histone H3 (Acetyl Lys23) Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and analysis of acetylated Lysine 23 residue on Histone H3. This antibody is produced using advanced immunization techniques, ensuring high affinity and specificity towards the target antigen.\u003cbr\u003e\u003cbr\u003eHistone H3 is a crucial component of chromatin structure and plays a vital role in gene regulation and DNA packaging. Acetylation of Lysine 23 on Histone H3 has been implicated in various biological processes, including transcriptional activation and chromatin remodeling. Therefore, the detection and quantification of acetylated Lysine 23 on Histone H3 are of great importance in understanding the epigenetic regulation of gene expression.\u003cbr\u003e\u003cbr\u003eThe Histone H3 (Acetyl Lys23) Polyclonal Antibody exhibits exceptional sensitivity and specificity, enabling accurate detection and quantification of acetylated Lysine 23 on Histone H3 in various biological samples. It has been extensively validated for use in Western blotting, immunohistochemistry, and chromatin immunoprecipitation assays.\u003cbr\u003e\u003cbr\u003eThis antibody is produced using high-quality materials and undergoes rigorous quality control procedures to ensure consistent performance and reliability. It is supplied as a liquid formulation, ready for immediate use, and is compatible with a wide range of experimental conditions.\u003cbr\u003e\u003cbr\u003eIn summary, the Histone H3 (Acetyl Lys23) Polyclonal Antibody is a valuable tool for researchers studying epigenetic modifications and gene regulation. Its high specificity, sensitivity, and versatility make it an ideal choice for various applications, including protein analysis, cellular imaging, and epigenetic research.\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"100ul \/ Rabbit \/ Primary antibody","offer_id":47541761605912,"sku":"BT-AP04039","price":275.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/BT_Lab_bd2b2c3e-3935-4da7-9b72-557563f19f55.png?v=1705624407","url":"https:\/\/danabiosci.com\/products\/new-product-568373","provider":"Dana Bioscience","version":"1.0","type":"link"}