{"product_id":"new-product-568356","title":"Histone H2B (Di Methyl Lys43) Polyclonal Antibody","description":"\u003cp\u003eHistones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. HIST1H2BA is intronless and encodes a replication-dependent histone that is a testis\/sperm-specific member of the histone H2B family. Transcripts from HIST1H2BA contain a palindromic termination element.\u003c\/p\u003e\n\u003cp\u003eThe Histone H2B (Di Methyl Lys43) Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and analysis of histone H2B protein modifications. This antibody is produced using advanced polyclonal antibody technology, ensuring high affinity and specificity towards the di methylated lysine 43 residue of histone H2B. \u003cbr\u003e\u003cbr\u003eHistone H2B is a crucial component of the nucleosome, playing a vital role in chromatin structure and gene regulation. The di methylation of lysine 43 on histone H2B has been implicated in various biological processes, including transcriptional activation and DNA repair. Therefore, the ability to accurately detect and quantify this modification is of utmost importance in understanding the underlying mechanisms of these processes.\u003cbr\u003e\u003cbr\u003eThe Histone H2B (Di Methyl Lys43) Polyclonal Antibody offers exceptional performance in various applications, including Western blotting, immunoprecipitation, and immunofluorescence. It exhibits minimal cross-reactivity with other histone modifications, ensuring reliable and specific results. Furthermore, this antibody has been extensively validated in multiple cell lines and tissues, guaranteeing consistent and reproducible data.\u003cbr\u003e\u003cbr\u003eWith its high sensitivity and specificity, the Histone H2B (Di Methyl Lys43) Polyclonal Antibody is an indispensable tool for researchers studying epigenetics, chromatin biology, and gene regulation. Its reliable performance and versatility make it an ideal choice for a wide range of applications, enabling in-depth investigations into the role of histone H2B di methylation in various biological processes.\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"100ul \/ Rabbit \/ Primary antibody","offer_id":47541756068120,"sku":"BT-AP04019","price":275.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/BT_Lab_19b270f6-45e9-48dd-8577-3a2fdc767a5f.png?v=1705624292","url":"https:\/\/danabiosci.com\/products\/new-product-568356","provider":"Dana Bioscience","version":"1.0","type":"link"}