{"product_id":"new-product-568352","title":"Histone H2B (Acetyl Lys20) Polyclonal Antibody","description":"\u003cp\u003eHistones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. HIST1H2BA is intronless and encodes a replication-dependent histone that is a testis\/sperm-specific member of the histone H2B family. Transcripts from HIST1H2BA contain a palindromic termination element.\u003c\/p\u003e\n\u003cp\u003eThe Histone H2B (Acetyl Lys20) Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and analysis of acetylated Lysine 20 on Histone H2B. This antibody is produced using a polyclonal approach, ensuring a diverse population of antibodies that can recognize and bind to the target antigen with high affinity and specificity.\u003cbr\u003e\u003cbr\u003eHistone H2B is a core histone protein that plays a crucial role in chromatin structure and gene regulation. Acetylation of Lysine 20 on Histone H2B has been implicated in various biological processes, including transcriptional activation and DNA repair. Therefore, the detection and quantification of acetylated Lysine 20 on Histone H2B is of great importance in understanding the epigenetic regulation of gene expression.\u003cbr\u003e\u003cbr\u003eThe Histone H2B (Acetyl Lys20) Polyclonal Antibody has been extensively validated for its performance in various applications, including Western blotting, immunohistochemistry, and chromatin immunoprecipitation. It exhibits high sensitivity and specificity, allowing for accurate and reliable detection of acetylated Lysine 20 on Histone H2B in various biological samples.\u003cbr\u003e\u003cbr\u003eThis antibody is supplied as a liquid formulation, ready for immediate use. It is provided in a convenient size and quantity, ensuring cost-effectiveness and minimizing waste. The Histone H2B (Acetyl Lys20) Polyclonal Antibody is manufactured under strict quality control standards, guaranteeing batch-to-batch consistency and reproducibility.\u003cbr\u003e\u003cbr\u003eIn summary, the Histone H2B (Acetyl Lys20) Polyclonal Antibody is a valuable tool for researchers studying epigenetic modifications and gene regulation. Its high specificity, sensitivity, and versatility make it an ideal choice for a wide range of applications, enabling accurate and reliable detection of acetylated Lysine 20 on Histone H2B.\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"100ul \/ Rabbit \/ Primary antibody","offer_id":47541754462488,"sku":"BT-AP04013","price":275.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/BT_Lab_25ae5c3c-8ff8-4416-b97b-fc52de0bcfb9.png?v=1705624265","url":"https:\/\/danabiosci.com\/products\/new-product-568352","provider":"Dana Bioscience","version":"1.0","type":"link"}