{"product_id":"new-product-568308","title":"Hexb Polyclonal Antibody","description":"\u003cp\u003eHexosaminidase B is the beta subunit of the lysosomal enzyme beta-hexosaminidase that, together with the cofactor GM2 activator protein, catalyzes the degradation of the ganglioside GM2, and other molecules containing terminal N-acetyl hexosamines. Beta-hexosaminidase is composed of two subunits, alpha and beta, which are encoded by separate genes. Both beta-hexosaminidase alpha and beta subunits are members of family 20 of glycosyl hydrolases. Mutations in the alpha or beta subunit genes lead to an accumulation of GM2 ganglioside in neurons and neurodegenerative disorders termed the GM2 gangliosidoses. Beta subunit gene mutations lead to Sandhoff disease (GM2-gangliosidosis type II). Alternatively spliced transcript variants encoding different isoforms have been found for HEXB.\u003c\/p\u003e\n\u003cp\u003eThe Hexb Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and quantification of Hexb protein in various biological samples. This antibody is produced through a rigorous process of immunization and purification, ensuring its high affinity and specificity towards Hexb. \u003cbr\u003e\u003cbr\u003eHexb, also known as beta-hexosaminidase subunit beta, is an essential enzyme involved in the degradation of glycosphingolipids. Dysregulation of Hexb has been implicated in various diseases, including lysosomal storage disorders and neurodegenerative diseases. Therefore, accurate measurement of Hexb levels is crucial for understanding the underlying mechanisms and developing therapeutic interventions.\u003cbr\u003e\u003cbr\u003eThe Hexb Polyclonal Antibody exhibits exceptional performance in a wide range of applications, including Western blotting, immunohistochemistry, and enzyme-linked immunosorbent assay (ELISA). It recognizes both native and denatured forms of Hexb, allowing for versatile and reliable detection across different experimental conditions.\u003cbr\u003e\u003cbr\u003eThis antibody is manufactured using state-of-the-art techniques and undergoes stringent quality control measures to ensure batch-to-batch consistency and reproducibility. It is supplied as a liquid formulation, ready for immediate use without the need for reconstitution or additional preparation steps.\u003cbr\u003e\u003cbr\u003eWith its superior sensitivity and specificity, the Hexb Polyclonal Antibody is an indispensable tool for researchers and clinicians working in the fields of molecular biology, biochemistry, and medicine. It enables accurate and precise quantification of Hexb protein levels, facilitating a deeper understanding of its role in disease pathogenesis and aiding in the development of targeted therapies.\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"100ul \/ Rabbit \/ Primary antibody","offer_id":47541736997144,"sku":"BT-AP03952","price":275.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/BT_Lab_f04f491d-0456-43fb-9973-6aca2ae3244a.png?v=1705624028","url":"https:\/\/danabiosci.com\/products\/new-product-568308","provider":"Dana Bioscience","version":"1.0","type":"link"}