{"product_id":"new-product-568053","title":"GDF-8 Polyclonal Antibody","description":"\u003cp\u003eMSTN encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein negatively regulates skeletal muscle cell proliferation and differentiation. Mutations in this gene are associated with increased skeletal muscle mass in humans and other mammals.\u003c\/p\u003e\n\u003cp\u003eThe GDF-8 Polyclonal Antibody is a highly specific and sensitive immunological tool designed for the detection and quantification of Growth Differentiation Factor 8 (GDF-8) protein. This antibody is produced through a rigorous and meticulous process, ensuring its high affinity and specificity towards GDF-8. \u003cbr\u003e\u003cbr\u003eGDF-8, also known as myostatin, is a member of the transforming growth factor-beta (TGF-β) superfamily and plays a crucial role in regulating skeletal muscle growth and development. Dysregulation of GDF-8 has been implicated in various muscular disorders, making it an important target for research and diagnostic purposes.\u003cbr\u003e\u003cbr\u003eThe GDF-8 Polyclonal Antibody exhibits exceptional performance in various applications, including Western blotting, immunohistochemistry, and enzyme-linked immunosorbent assay (ELISA). Its superior sensitivity allows for the detection of even low levels of GDF-8 protein, enabling accurate quantification and analysis.\u003cbr\u003e\u003cbr\u003eThis antibody is manufactured using state-of-the-art techniques and undergoes stringent quality control measures to ensure batch-to-batch consistency and reliability. It is supplied as a liquid formulation, ready for immediate use, eliminating the need for time-consuming reconstitution.\u003cbr\u003e\u003cbr\u003eThe GDF-8 Polyclonal Antibody is compatible with a wide range of sample types, including tissue lysates, cell lysates, and serum, facilitating its versatility and applicability in diverse research settings. Its robust performance and high specificity make it an indispensable tool for scientists and researchers studying muscle development, regeneration, and related disorders.\u003cbr\u003e\u003cbr\u003eIn summary, the GDF-8 Polyclonal Antibody is a premium immunological reagent that offers exceptional sensitivity, specificity, and versatility for the detection and quantification of GDF-8 protein. Its reliable performance and ease of use make it an invaluable asset in various research and diagnostic applications.\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"100ul \/ Rabbit \/ Primary antibody","offer_id":47541610938648,"sku":"BT-AP03535","price":275.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/BT_Lab_af4c6c67-bf2a-4569-af9a-2ac78b6b9062.png?v=1705622566","url":"https:\/\/danabiosci.com\/products\/new-product-568053","provider":"Dana Bioscience","version":"1.0","type":"link"}