{"product_id":"new-product-567802","title":"FAS Polyclonal Antibody","description":"\u003cp\u003eFas cell surface death receptor encoded by FAS is a member of the TNF-receptor superfamily. This receptor contains a death domain. It has been shown to play a central role in the physiological regulation of programmed cell death, and has been implicated in the pathogenesis of various malignancies and diseases of the immune system. The interaction of this receptor with its ligand allows the formation of a death-inducing signaling complex that includes Fas-associated death domain protein (FADD), caspase 8, and caspase 10. The autoproteolytic processing of the caspases in the complex triggers a downstream caspase cascade, and leads to apoptosis. This receptor has been also shown to activate NF-kappaB, MAPK3\/ERK1, and MAPK8\/JNK, and is found to be involved in transducing the proliferating signals in normal diploid fibroblast and T cells. Several alternatively spliced transcript variants have been described, some of which are candidates for nonsense-mediated mRNA decay (NMD). The isoforms lacking the transmembrane domain may negatively regulate the apoptosis mediated by the full length isoform.\u003c\/p\u003e\n\u003cp\u003eThe FAS Polyclonal Antibody is a highly specific and sensitive immunological tool designed for the detection and quantification of FAS protein expression. This antibody is produced using a polyclonal approach, ensuring a diverse range of antibodies that recognize different epitopes on the FAS protein. \u003cbr\u003e\u003cbr\u003eThe FAS Polyclonal Antibody exhibits exceptional affinity and selectivity, enabling accurate and reliable results in various applications such as Western blotting, immunohistochemistry, and flow cytometry. Its superior sensitivity allows for the detection of even low levels of FAS protein expression, making it an invaluable tool for researchers studying apoptosis and cell death pathways.\u003cbr\u003e\u003cbr\u003eThis antibody is manufactured using state-of-the-art techniques and undergoes rigorous quality control measures to ensure consistent performance and reproducibility. It is supplied as a ready-to-use solution, eliminating the need for time-consuming and error-prone antibody preparation.\u003cbr\u003e\u003cbr\u003eThe FAS Polyclonal Antibody is compatible with a wide range of sample types, including cell lysates, tissue sections, and cultured cells. Its versatility and robustness make it suitable for use in various research fields, including cancer biology, immunology, and molecular biology.\u003cbr\u003e\u003cbr\u003eChoose the FAS Polyclonal Antibody for its exceptional performance, reliability, and ease of use. Accelerate your research and gain valuable insights into the intricate mechanisms of apoptosis with this high-quality immunological tool.\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"100ul \/ Rabbit \/ Primary antibody","offer_id":47541481701656,"sku":"BT-AP03162","price":275.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/BT_Lab_32ba651a-a7df-418d-9b81-8341076eb60e.png?v=1705620429","url":"https:\/\/danabiosci.com\/products\/new-product-567802","provider":"Dana Bioscience","version":"1.0","type":"link"}