{"product_id":"new-product-567698","title":"EphB2 Polyclonal Antibody","description":"\u003cp\u003eEPHB2 encodes a member of the Eph receptor family of receptor tyrosine kinase transmembrane glycoproteins. These receptors are composed of an N-terminal glycosylated ligand-binding domain, a transmembrane region and an intracellular kinase domain. They bind ligands called ephrins and are involved in diverse cellular processes including motility, division, and differentiation. A distinguishing characteristic of Eph-ephrin signaling is that both receptors and ligands are competent to transduce a signaling cascade, resulting in bidirectional signaling. This protein belongs to a subgroup of the Eph receptors called EphB. Proteins of this subgroup are distinguished from other members of the family by sequence homology and preferential binding affinity for membrane-bound ephrin-B ligands. Allelic variants are associated with prostate and brain cancer susceptibility. Alternative splicing results in multiple transcript variants.\u003c\/p\u003e\n\u003cp\u003eThe EphB2 Polyclonal Antibody is a highly specific and sensitive antibody designed for the detection of EphB2 protein in various biological samples. This antibody is produced by immunizing rabbits with a synthetic peptide corresponding to the C-terminal region of human EphB2 protein. The antibody has been purified using protein A affinity chromatography and is supplied as a liquid solution in phosphate-buffered saline (PBS) with 0.02% sodium azide as a preservative.\u003cbr\u003e\u003cbr\u003eThe EphB2 Polyclonal Antibody has been extensively validated for its specificity and sensitivity in various applications, including Western blotting, immunohistochemistry, and immunofluorescence. It recognizes both the full-length and cleaved forms of EphB2 protein and has been shown to cross-react with EphB2 from various species, including human, mouse, and rat.\u003cbr\u003e\u003cbr\u003eThis antibody is an essential tool for researchers studying the role of EphB2 in various biological processes, including cell adhesion, migration, and differentiation. It can also be used for diagnostic purposes in the detection of EphB2 expression in cancer tissues.\u003cbr\u003e\u003cbr\u003eIn summary, the EphB2 Polyclonal Antibody is a reliable and high-quality antibody that provides accurate and reproducible results in various applications. Its specificity and sensitivity make it an ideal tool for researchers and clinicians studying EphB2 protein expression and function.\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"100ul \/ Rabbit \/ Primary antibody","offer_id":47541449261336,"sku":"BT-AP03009","price":275.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/BT_Lab_ee2f5708-1460-4039-9fea-e4d10675bdc5.png?v=1705619832","url":"https:\/\/danabiosci.com\/products\/new-product-567698","provider":"Dana Bioscience","version":"1.0","type":"link"}