{"product_id":"new-product-567542","title":"Dyrk1A Polyclonal Antibody","description":"\u003cp\u003eDYRK1A encodes a member of the Dual-specificity tyrosine phosphorylation-regulated kinase (DYRK) family. This member contains a nuclear targeting signal sequence, a protein kinase domain, a leucine zipper motif, and a highly conservative 13-consecutive-histidine repeat. It catalyzes its autophosphorylation on serine\/threonine and tyrosine residues. It may play a significant role in a signaling pathway regulating cell proliferation and may be involved in brain development. DYRK1A is a homolog of Drosophila mnb (minibrain) gene and rat Dyrk gene. It is localized in the Down syndrome critical region of chromosome 21, and is considered to be a strong candidate gene for learning defects associated with Down syndrome. Alternative splicing of DYRK1A generates several transcript variants differing from each other either in the 5' UTR or in the 3' coding region. These variants encode at least five different isoforms.\u003c\/p\u003e\n\u003cp\u003eThe Dyrk1A Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and analysis of Dyrk1A protein expression in various biological samples. This antibody has been meticulously developed and rigorously validated to ensure optimal performance and reliability in a wide range of applications, including Western blotting, immunohistochemistry, and immunofluorescence.\u003cbr\u003e\u003cbr\u003eWith its exceptional affinity and selectivity, this polyclonal antibody exhibits minimal cross-reactivity with other proteins, enabling accurate and precise quantification of Dyrk1A levels. Its high sensitivity allows for the detection of even low-abundance Dyrk1A protein, making it an invaluable tool for researchers studying the role of Dyrk1A in various cellular processes and diseases.\u003cbr\u003e\u003cbr\u003eThe Dyrk1A Polyclonal Antibody is produced using state-of-the-art techniques, ensuring batch-to-batch consistency and reproducibility. It is supplied as a liquid formulation, ready for immediate use, eliminating the need for time-consuming reconstitution. The antibody is provided in a convenient size, allowing for multiple experiments and minimizing wastage.\u003cbr\u003e\u003cbr\u003eFurthermore, this antibody has been extensively tested and validated in various cell lines and tissues, guaranteeing its reliability and accuracy. Its robust performance in different experimental conditions and sample types ensures consistent and dependable results, facilitating meaningful data interpretation and analysis.\u003cbr\u003e\u003cbr\u003eIn summary, the Dyrk1A Polyclonal Antibody is a superior research tool that offers exceptional sensitivity, specificity, and reliability for the detection and analysis of Dyrk1A protein expression. Its high performance and versatility make it an indispensable asset for researchers in the fields of molecular biology, biochemistry, and biomedical research.\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"100ul \/ Rabbit \/ Primary antibody","offer_id":47541403812120,"sku":"BT-AP02774","price":275.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/BT_Lab_4abd3ac0-9978-4024-9b54-8fd166214b1c.png?v=1705618945","url":"https:\/\/danabiosci.com\/products\/new-product-567542","provider":"Dana Bioscience","version":"1.0","type":"link"}