{"product_id":"new-product-567510","title":"Doublecortin Polyclonal Antibody","description":"\u003cp\u003eDCX encodes a member of the doublecortin family. Neuronal migration protein doublecortin encoded by DCX is a cytoplasmic protein and contains two doublecortin domains, which bind microtubules. In the developing cortex, cortical neurons must migrate over long distances to reach the site of their final differentiation. The encoded protein appears to direct neuronal migration by regulating the organization and stability of microtubules. In addition, the encoded protein interacts with LIS1, the regulatory gamma subunit of platelet activating factor acetylhydrolase, and this interaction is important to proper microtubule function in the developing cortex. Mutations in this gene cause abnormal migration of neurons during development and disrupt the layering of the cortex, leading to epilepsy, mental retardation, subcortical band heterotopia (\"double cortex\" syndrome) in females and lissencephaly (\"smooth brain\" syndrome) in males. Multiple transcript variants encoding different isoforms have been found for this gene.\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eThe Doublecortin Polyclonal Antibody is a highly specific and reliable tool designed for the detection and analysis of doublecortin protein expression in various biological samples. This antibody is produced using advanced immunization techniques, ensuring high affinity and sensitivity towards the target protein. With its exceptional specificity, this polyclonal antibody enables accurate identification and localization of doublecortin in tissues and cells. It has been extensively validated in a wide range of applications, including immunohistochemistry, immunofluorescence, and Western blotting. \u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eThe Doublecortin Polyclonal Antibody exhibits excellent performance in terms of signal intensity and low background noise, allowing for precise and reliable results. Its superior quality and consistency make it an ideal choice for researchers and scientists working in the fields of neuroscience, developmental biology, and neurology. This antibody is supplied as a liquid formulation, ready for immediate use. \u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eIt is provided in a convenient size, ensuring cost-effectiveness and minimizing waste. Each batch undergoes rigorous quality control procedures to guarantee batch-to-batch consistency and reproducibility. In summary, the Doublecortin Polyclonal Antibody offers exceptional specificity, sensitivity, and reliability for the detection and analysis of doublecortin protein expression. Its superior performance and ease of use make it an indispensable tool for researchers seeking to unravel the intricate mechanisms underlying neurodevelopment and neurological disorders.\u003c\/span\u003e\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"100ul \/ Rabbit \/ Primary antibody","offer_id":47541395783960,"sku":"BT-AP02708","price":275.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/BT_Lab_645e79e9-5ecf-41a9-933b-28a28b35d5b7.png?v=1705618786","url":"https:\/\/danabiosci.com\/products\/new-product-567510","provider":"Dana Bioscience","version":"1.0","type":"link"}