{"product_id":"new-product-567480","title":"DNA pol iota Polyclonal Antibody","description":"\u003cp\u003ePOLI (Polymerase (DNA) Iota) is a Protein Coding gene. Among its related pathways are DNA Double-Strand Break Repair and Fanconi anemia pathway. GO annotations related to this gene include damaged DNA binding and DNA-directed DNA polymerase activity. An important paralog of this gene is POLH. rror-prone DNA polymerase specifically involved in DNA repair. Plays an important role in translesion synthesis, where the normal high-fidelity DNA polymerases cannot proceed and DNA synthesis stalls. Favors Hoogsteen base-pairing in the active site. Inserts the correct base with high-fidelity opposite an adenosine template. Exhibits low fidelity and efficiency opposite a thymidine template, where it will preferentially insert guanosine. May play a role in hypermutation of immunogobulin genes. Forms a Schiff base with 5-deoxyribose phosphate at abasic sites, but may not have lyase activity.\u003c\/p\u003e\n\u003cp\u003eThe DNA pol iota Polyclonal Antibody is a highly specific and sensitive antibody that has been designed to detect and quantify the presence of DNA polymerase iota (pol iota) in various biological samples. This antibody has been produced using high-quality polyclonal antibodies that have been purified and validated to ensure optimal performance and reliability.\u003cbr\u003e\u003cbr\u003eThe DNA pol iota Polyclonal Antibody is suitable for use in a wide range of applications, including Western blotting, immunohistochemistry, and immunofluorescence. It has been extensively tested and validated to ensure that it provides accurate and reproducible results, making it an ideal tool for researchers and scientists working in the field of DNA replication and repair.\u003cbr\u003e\u003cbr\u003eThis antibody is supplied in a convenient and easy-to-use format, with clear instructions for use provided with each product. It is available in a range of sizes to suit different experimental requirements, and can be used in combination with other antibodies and reagents to achieve optimal results.\u003cbr\u003e\u003cbr\u003eOverall, the DNA pol iota Polyclonal Antibody is a high-quality and reliable tool for the detection and quantification of DNA polymerase iota in biological samples. Its sensitivity, specificity, and ease of use make it an ideal choice for researchers and scientists working in a variety of fields, including molecular biology, genetics, and biochemistry.\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"100ul \/ Rabbit \/ Primary antibody","offer_id":47541385593112,"sku":"BT-AP02665","price":275.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/BT_Lab_c4e75924-3fe5-4f91-9c80-2ba65d091ed5.png?v=1705618618","url":"https:\/\/danabiosci.com\/products\/new-product-567480","provider":"Dana Bioscience","version":"1.0","type":"link"}