{"product_id":"new-product-567365","title":"Cytokeratin 8 Polyclonal Antibody","description":"\u003cp\u003eKRT8 is a member of the type II keratin family clustered on the long arm of chromosome 12. Type I and type II keratins heteropolymerize to form intermediate-sized filaments in the cytoplasm of epithelial cells. The product of this gene typically dimerizes with keratin 18 to form an intermediate filament in simple single-layered epithelial cells. This protein plays a role in maintaining cellular structural integrity and also functions in signal transduction and cellular differentiation. Mutations in this gene cause cryptogenic cirrhosis. Alternatively spliced transcript variants have been found for this gene.\u003c\/p\u003e\n\u003cp\u003eThe CYP2C8 Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and quantification of CYP2C8 protein expression. This antibody is produced through a rigorous process, ensuring its high affinity and specificity towards the target protein. \u003cbr\u003e\u003cbr\u003eCYP2C8, a member of the cytochrome P450 superfamily, plays a crucial role in the metabolism of various endogenous and exogenous compounds, including drugs and xenobiotics. Its expression has been implicated in the metabolism and clearance of numerous pharmaceutical agents, making it a significant target for drug development and personalized medicine.\u003cbr\u003e\u003cbr\u003eThe CYP2C8 Polyclonal Antibody exhibits exceptional performance in various applications, including Western blotting, immunohistochemistry, and immunofluorescence. It enables researchers to investigate the expression and localization of CYP2C8 in different tissues and cell types, facilitating a deeper understanding of its physiological and pathological roles.\u003cbr\u003e\u003cbr\u003eWith its high sensitivity and specificity, this antibody offers reliable and reproducible results, ensuring accurate data interpretation. It is manufactured under strict quality control standards, guaranteeing batch-to-batch consistency and optimal performance. Additionally, it is validated for use in multiple species, including human, mouse, and rat, broadening its applicability in diverse research settings.\u003cbr\u003e\u003cbr\u003eIn summary, the CYP2C8 Polyclonal Antibody is an indispensable tool for researchers studying drug metabolism, personalized medicine, and the role of CYP2C8 in various physiological and pathological processes. Its exceptional performance, reliability, and versatility make it an ideal choice for scientists seeking to unravel the complexities of CYP2C8 protein expression and function.\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"100ul \/ Rabbit \/ Primary antibody","offer_id":47541349155096,"sku":"BT-AP02477","price":275.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/BT_Lab_d96f9dec-a1d7-467a-ad1e-9c0b4c63c279.png?v=1705617995","url":"https:\/\/danabiosci.com\/products\/new-product-567365","provider":"Dana Bioscience","version":"1.0","type":"link"}