{"product_id":"new-product-567201","title":"Crystallin- AlphaB Polyclonal Antibody","description":"\u003cp\u003eMammalian lens crystallins are divided into alpha, beta, and gamma families. Alpha crystallins are composed of two gene products: alpha-A and alpha-B, for acidic and basic, respectively. Alpha crystallins can be induced by heat shock and are members of the small heat shock protein (HSP20) family. They act as molecular chaperones although they do not renature proteins and release them in the fashion of a true chaperone; instead they hold them in large soluble aggregates. Post-translational modifications decrease the ability to chaperone. These heterogeneous aggregates consist of 30-40 subunits; the alpha-A and alpha-B subunits have a 3:1 ratio, respectively. Two additional functions of alpha crystallins are an autokinase activity and participation in the intracellular architecture. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. Alpha-A and alpha-B gene products are differentially expressed; alpha-A is preferentially restricted to the lens and alpha-B is expressed widely in many tissues and organs. Elevated expression of alpha-B crystallin occurs in many neurological diseases; a missense mutation cosegregated in a family with a desmin-related myopathy. Alternative splicing results in multiple transcript variants.\u003c\/p\u003e\n\u003cp\u003eIntroducing the Crystallin-ALPHAB Polyclonal Antibody, a cutting-edge product meticulously designed to cater to the diverse needs of the scientific community. This highly specialized antibody is crafted with utmost precision and expertise, ensuring unparalleled accuracy and reliability in its performance.\u003cbr\u003e\u003cbr\u003eThe Crystallin-ALPHAB Polyclonal Antibody is specifically engineered to target and detect the Crystallin-ALPHAB protein, a crucial component in various biological processes. With its exceptional affinity and specificity, this antibody offers an invaluable tool for researchers and scientists alike, enabling them to delve deeper into the intricate mechanisms underlying cellular functions.\u003cbr\u003e\u003cbr\u003eThrough rigorous quality control measures, the Crystallin-ALPHAB Polyclonal Antibody guarantees consistent and reproducible results, empowering researchers to obtain robust and meaningful data. Its exceptional sensitivity and low background noise further enhance its utility, facilitating the detection of even the most minute quantities of the Crystallin-ALPHAB protein.\u003cbr\u003e\u003cbr\u003eMoreover, this antibody is manufactured using state-of-the-art techniques and adheres to the highest industry standards, ensuring optimal performance and longevity. Its long shelf life and stability make it an ideal choice for long-term experiments and extended research projects.\u003cbr\u003e\u003cbr\u003eThe Crystallin-ALPHAB Polyclonal Antibody is supplied in a convenient and user-friendly format, allowing for easy integration into various experimental protocols. Its versatility extends to a wide range of applications, including Western blotting, immunohistochemistry, and immunofluorescence, enabling researchers to explore diverse avenues of scientific inquiry.\u003cbr\u003e\u003cbr\u003eIn summary, the Crystallin-ALPHAB Polyclonal Antibody represents a pinnacle of scientific innovation, offering an indispensable tool for elucidating the intricate workings of cellular processes. With its exceptional performance, reliability, and versatility, this antibody is poised to revolutionize the field of molecular biology and empower researchers in their quest for scientific advancement.\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"100ul \/ Rabbit \/ Primary antibody","offer_id":47541296759064,"sku":"BT-AP02260","price":275.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/BT_Lab_c727acd4-b736-4464-93b9-efe437bf394b.png?v=1705617098","url":"https:\/\/danabiosci.com\/products\/new-product-567201","provider":"Dana Bioscience","version":"1.0","type":"link"}