{"product_id":"new-product-567175","title":"c-Rel Polyclonal Antibody","description":"\u003cp\u003eREL (REL proto-oncogene, NF-kB subunit) encodes a protein that belongs to the Rel homology domain\/immunoglobulin-like fold, plexin, transcription factor (RHD\/IPT) family. Members of this family regulate genes involved in apoptosis, inflammation, the immune response, and oncogenic processes. This proto-oncogene plays a role in the survival and proliferation of B lymphocytes. Mutation or amplification of REL is associated with B-cell lymphomas, including Hodgkin's lymphoma. Single nucleotide polymorphisms in REL are associated with susceptibility to ulcerative colitis and rheumatoid arthritis. Alternative splicing results in multiple transcript variants encoding different isoforms.\u003c\/p\u003e\n\u003cp\u003eThe c-Rel Polyclonal Antibody is a highly specific and sensitive antibody that has been designed for use in various research applications. This antibody is produced by immunizing rabbits with a synthetic peptide corresponding to the C-terminal region of human c-Rel protein. The resulting polyclonal antibody has been purified using protein A affinity chromatography and is suitable for use in Western blotting, immunohistochemistry, and immunofluorescence assays.\u003cbr\u003e\u003cbr\u003eThe c-Rel Polyclonal Antibody has been extensively validated for its specificity and sensitivity in detecting c-Rel protein in various cell types and tissues. It has been shown to recognize both the full-length and truncated forms of c-Rel protein, making it a versatile tool for studying the function and regulation of this important transcription factor.\u003cbr\u003e\u003cbr\u003eThis antibody is supplied as a liquid in phosphate-buffered saline (PBS) containing 0.02% sodium azide as a preservative. It is recommended to store the antibody at -20°C for long-term storage and to avoid repeated freeze-thaw cycles.\u003cbr\u003e\u003cbr\u003eIn summary, the c-Rel Polyclonal Antibody is a reliable and high-quality reagent that can be used for a wide range of research applications. Its specificity and sensitivity make it an ideal tool for studying the role of c-Rel in various biological processes.\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"100ul \/ Rabbit \/ Primary antibody","offer_id":47541290533144,"sku":"BT-AP02220","price":275.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/BT_Lab_2914689c-aea5-4c25-8b9c-6ed9d95b45a4.png?v=1705616949","url":"https:\/\/danabiosci.com\/products\/new-product-567175","provider":"Dana Bioscience","version":"1.0","type":"link"}