{"product_id":"new-product-567102","title":"COMT Polyclonal Antibody","description":"\u003cp\u003eCatechol-O-methyltransferase catalyzes the transfer of a methyl group from S-adenosylmethionine to catecholamines, including the neurotransmitters dopamine, epinephrine, and norepinephrine. This O-methylation results in one of the major degradative pathways of the catecholamine transmitters. In addition to its role in the metabolism of endogenous substances, COMT is important in the metabolism of catechol drugs used in the treatment of hypertension, asthma, and Parkinson disease. COMT is found in two forms in tissues, a soluble form (S-COMT) and a membrane-bound form (MB-COMT). The differences between S-COMT and MB-COMT reside within the N-termini. Several transcript variants are formed through the use of alternative translation initiation sites and promoters.\u003c\/p\u003e\n\u003cp\u003eThe COP1 Polyclonal Antibody is a highly specific and sensitive antibody designed for use in various research applications. This antibody is produced by immunizing rabbits with a synthetic peptide corresponding to the C-terminus of the COP1 protein. The COP1 Polyclonal Antibody has been extensively validated for its specificity and sensitivity in Western blotting, immunohistochemistry, and immunofluorescence assays.\u003cbr\u003e\u003cbr\u003eThe COP1 protein is a key regulator of various cellular processes, including cell cycle progression, DNA damage response, and apoptosis. Dysregulation of COP1 has been implicated in the development and progression of various diseases, including cancer. The COP1 Polyclonal Antibody is an essential tool for researchers studying the role of COP1 in these processes.\u003cbr\u003e\u003cbr\u003eThe COP1 Polyclonal Antibody is supplied as a purified IgG fraction, which has been affinity-purified using immobilized protein A. This antibody is provided in a liquid format, which is ready to use for various applications. The COP1 Polyclonal Antibody is highly specific and sensitive, with minimal cross-reactivity with other proteins.\u003cbr\u003e\u003cbr\u003eIn summary, the COP1 Polyclonal Antibody is a highly specific and sensitive antibody that is essential for researchers studying the role of COP1 in various cellular processes. This antibody is extensively validated and supplied in a purified IgG fraction, making it an ideal tool for various research applications.\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"100ul \/ Rabbit \/ Primary antibody","offer_id":47541268611352,"sku":"BT-AP02107","price":275.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/BT_Lab_bc4e2d54-1c76-4f98-83b5-912450205b78.png?v=1705616554","url":"https:\/\/danabiosci.com\/products\/new-product-567102","provider":"Dana Bioscience","version":"1.0","type":"link"}