{"product_id":"new-product-567002","title":"Cleaved-Notch 4 (V1432) Polyclonal Antibody","description":"\u003cp\u003eNOTCH4 encodes a member of the NOTCH family of proteins. Members of this Type I transmembrane protein family share structural characteristics including an extracellular domain consisting of multiple epidermal growth factor-like (EGF) repeats, and an intracellular domain consisting of multiple different domain types. Notch signaling is an evolutionarily conserved intercellular signaling pathway that regulates interactions between physically adjacent cells through binding of Notch family receptors to their cognate ligands. The encoded preproprotein is proteolytically processed in the trans-Golgi network to generate two polypeptide chains that heterodimerize to form the mature cell-surface receptor. This receptor may play a role in vascular, renal and hepatic development. Mutations in NOTCH4 may be associated with schizophrenia. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed.\u003c\/p\u003e\n\u003cp\u003eIntroducing the Cleaved-Notch 4 (V1432) Polyclonal Antibody, a cutting-edge scientific tool meticulously designed to facilitate advanced research in the field of molecular biology. This high-quality antibody is specifically engineered to target and detect the cleaved form of Notch 4, a crucial protein involved in various cellular processes.\u003cbr\u003e\u003cbr\u003eCrafted with utmost precision, the Cleaved-Notch 4 (V1432) Polyclonal Antibody exhibits exceptional specificity and sensitivity, ensuring accurate and reliable results. Its polyclonal nature enables it to recognize multiple epitopes, enhancing its versatility and enabling a wide range of applications, including immunohistochemistry, western blotting, and immunofluorescence.\u003cbr\u003e\u003cbr\u003eWith its superior performance, this antibody enables researchers to delve deeper into the intricate mechanisms underlying Notch 4 signaling pathways. By precisely detecting the cleaved form of Notch 4, it provides invaluable insights into cellular processes such as cell differentiation, proliferation, and apoptosis.\u003cbr\u003e\u003cbr\u003eThe Cleaved-Notch 4 (V1432) Polyclonal Antibody is meticulously manufactured using state-of-the-art techniques and undergoes rigorous quality control measures to ensure optimal performance and consistency. Its exceptional stability and long shelf life guarantee reliable results, making it an indispensable tool for both basic and clinical research.\u003cbr\u003e\u003cbr\u003eInvest in the Cleaved-Notch 4 (V1432) Polyclonal Antibody today and unlock new frontiers in molecular biology research. Stay at the forefront of scientific advancements with this cutting-edge antibody, empowering you to unravel the complexities of Notch 4 signaling and contribute to the advancement of biomedical knowledge.\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"100ul \/ Rabbit \/ Primary antibody","offer_id":47541237481752,"sku":"BT-AP01957","price":275.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/BT_Lab_ab7965e1-2101-45e3-8df1-833749751453.png?v=1705615926","url":"https:\/\/danabiosci.com\/products\/new-product-567002","provider":"Dana Bioscience","version":"1.0","type":"link"}