{"product_id":"new-product-566978","title":"Cleaved-Integrin  AlphaV HC (K889) Polyclonal Antibody","description":"\u003cp\u003eThe product of ITGAV belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha subunit and a beta subunit that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha V subunit. This subunit associates with beta 1, beta 3, beta 5, beta 6 and beta 8 subunits.\u003c\/p\u003e\n\u003cp\u003eThe heterodimer consisting of alpha V and beta 3 subunits is also known as the vitronectin receptor. This integrin may regulate angiogenesis and cancer progression. Alternative splicing results in multiple transcript variants. Note that the integrin alpha 5 and integrin alpha V subunits are encoded by distinct genes.\u003c\/p\u003e\n\u003cp\u003eThe Cleaved-Integrin AlphaV HC (K889) Polyclonal Antibody is a highly specific and sensitive immunological reagent designed for the detection and quantification of cleaved-integrin alphaV HC (K889) in various biological samples.\u003c\/p\u003e\n\u003cp\u003eThis antibody is produced by immunizing rabbits with a synthetic peptide corresponding to the cleaved-integrin alphaV HC (K889) sequence and purified using protein A affinity chromatography. The Cleaved-Integrin AlphaV HC (K889) Polyclonal Antibody has been extensively validated for its specificity and sensitivity in various applications, including Western blotting, immunohistochemistry, and ELISA.\u003c\/p\u003e\n\u003cp\u003eThis antibody is suitable for use in both research and diagnostic applications and is an essential tool for investigating the role of cleaved-integrin alphaV HC (K889) in various physiological and pathological processes. With its high quality and reliability, the Cleaved-Integrin AlphaV HC (K889) Polyclonal Antibody is an indispensable reagent for researchers and clinicians alike.\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"100ul \/ Rabbit \/ Primary antibody","offer_id":47541229879576,"sku":"BT-AP01933","price":275.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/BT_Lab_113b94aa-c782-4f67-b2b3-10c0ffc75279.png?v=1705615773","url":"https:\/\/danabiosci.com\/products\/new-product-566978","provider":"Dana Bioscience","version":"1.0","type":"link"}