{"product_id":"new-product-566976","title":"Cleaved-Integrin  Alpha6 LC (E942) Polyclonal Antibody","description":"\u003cp\u003eITGA6 encodes a member of the integrin alpha chain family of proteins. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha 6 subunit. This subunit may associate with a beta 1 or beta 4 subunit to form an integrin that interacts with extracellular matrix proteins including members of the laminin family. The alpha 6 beta 4 integrin may promote tumorigenesis, while the alpha 6 beta 1 integrin may negatively regulate erbB2\/HER2 signaling. Alternative splicing results in multiple transcript variants.\u003c\/p\u003e\n\u003cp\u003eThe Cleaved-Integrin Alpha6 LC (E942) Polyclonal Antibody is a highly specific and sensitive immunological reagent designed for the detection and quantification of cleaved-integrin alpha6 LC in various biological samples. This antibody is produced using high-quality polyclonal antibodies that have been purified and validated to ensure optimal performance and reproducibility.\u003cbr\u003e\u003cbr\u003eThe Cleaved-Integrin Alpha6 LC (E942) Polyclonal Antibody is suitable for use in a wide range of applications, including Western blotting, immunohistochemistry, and immunofluorescence. It has been extensively tested and validated for its specificity and sensitivity, ensuring accurate and reliable results.\u003cbr\u003e\u003cbr\u003eThis antibody is supplied in a convenient and easy-to-use format, making it ideal for use in both research and clinical settings. It is available in various sizes to suit different experimental needs and can be used in combination with other antibodies and reagents for multiplexed analysis.\u003cbr\u003e\u003cbr\u003eOverall, the Cleaved-Integrin Alpha6 LC (E942) Polyclonal Antibody is a valuable tool for researchers and clinicians working in the fields of cancer biology, cell signaling, and integrin biology. Its high specificity, sensitivity, and versatility make it an essential reagent for the detection and quantification of cleaved-integrin alpha6 LC in various biological samples.\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"100ul \/ Rabbit \/ Primary antibody","offer_id":47541229715736,"sku":"BT-AP01931","price":275.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/BT_Lab_4223ee03-ffc7-4ebc-9b20-4631ddfab82a.png?v=1705615766","url":"https:\/\/danabiosci.com\/products\/new-product-566976","provider":"Dana Bioscience","version":"1.0","type":"link"}